| Round | Overall | Player |
|---|---|---|
| 1 | 10th | 1B Adrian Gonzalez Bos |
| 2 | 15th | 1B Mark Teixeira NYA |
| 3 | 34th | SP Jon Lester Bos |
| 4 | 39th | SP C.C. Sabathia NYA |
| 5 | 58th | SS Derek Jeter NYA |
| 6 | 63rd | SP Cole Hamels Phi |
| 7 | 82nd | 3B Pablo Sandoval SF |
| 8 | 87th | 2B Ben Zobrist TB |
| 9 | 106th | C Matt Wieters Bal |
| 10 | 111th | OF Corey Hart Mil |
| 11 | 130th | SP Jonathan Sanchez KC |
| 12 | 135th | SP Daniel Hudson Ari |
| 13 | 154th | RP John Axford Mil |
| 14 | 159th | RP Joe Nathan Tex |
| 15 | 178th | OF Michael Cuddyer Col |
| 16 | 183rd | OF Carlos Beltran STL |
| 17 | 202nd | SP Javier Vazquez Fla |
| 18 | 207th | OF Carlos Lee Hou |
| 19 | 226th | OF Ichiro Suzuki Sea |
| 20 | 231st | SP Rick Porcello Det |
| 21 | 250th | 2B Jose Lopez Cle |
| 22 | 255th | C Jesus Montero Sea |
| 23 | 274th | SP Michael Pineda NYA |
| 24 | 279th | OF Johnny Damon TB |
| 25 | 298th | 1B Lyle Overbay Ari |
| 26 | 303rd | 3B Mike Moustakas KC |
| 27 | 322nd | 3B Brandon Inge Det |
| 28 | 327th | SS Alcides Escobar KC |
| 29 | 346th | C Rod Barajas Pit |