| Round | Overall | Player |
|---|---|---|
| 1 | 12th | 3B Alex Rodriguez NYA |
| 2 | 13th | 1B Prince Fielder Mil |
| 3 | 36th | OF Matt Kemp LAD |
| 4 | 37th | 1B Justin Morneau Min |
| 5 | 60th | SP Yovani Gallardo Mil |
| 6 | 61st | OF Jay Bruce Cin |
| 7 | 84th | SP Max Scherzer Det |
| 8 | 85th | OF Chris Young Ari |
| 9 | 108th | SP Brett Anderson Oak |
| 10 | 109th | C Mike Napoli Tex |
| 11 | 132nd | SS Ian Desmond Was |
| 12 | 133rd | 1B Adam Lind Tor |
| 13 | 156th | 2B Neil Walker Pit |
| 14 | 157th | SP Ted Lilly LAD |
| 15 | 180th | SP Edison Volquez SD |
| 16 | 181st | RP Jose Valverde Det |
| 17 | 204th | RP J.J. Putz Ari |
| 18 | 205th | OF Jose Tabata Pit |
| 19 | 228th | RP Leo Nunez Fla |
| 20 | 229th | 2B Sean Rodriguez TB |
| 21 | 252nd | C Chris Iannetta LAA |
| 22 | 253rd | SP Ian Kennedy Ari |
| 23 | 276th | 3B Placido Polanco Phi |
| 24 | 277th | SS Reid Brignac TB |
| 25 | 300th | DH Edwin Encarnacion Tor |
| 26 | 301st | OF Seth Smith Oak |
| 27 | 324th | OF Mike Morse Was |
| 28 | 325th | SP Jonathon Niese NYN |
| 29 | 348th | SP James Mcdonald Pit |