| Round | Overall | Player |
|---|---|---|
| 1 | 7th | 1B Adrian Gonzalez LAD |
| 2 | 18th | OF Carlos Gonzalez Col |
| 3 | 31st | C Carlos Santana Cle |
| 4 | 42nd | 3B Alex Rodriguez NYA |
| 5 | 55th | OF Matt Holliday StL |
| 6 | 66th | SP Yovani Gallardo Mil |
| 7 | 79th | SP Matthew Moore TB |
| 8 | 90th | SP Yu Darvish Tex |
| 9 | 103rd | 1B Mark Reynolds Cle |
| 10 | 114th | OF Chris Young Oak |
| 11 | 127th | 2B Dustin Ackley Sea |
| 12 | 138th | SP Jeremy Hellickson TB |
| 13 | 151st | SP Johan Santana NYN |
| 14 | 162nd | RP Jason Motte StL |
| 15 | 175th | 3B Mike Moustakas KC |
| 16 | 186th | SS Yunel Escobar TB |
| 17 | 199th | OF Drew Stubbs Cle |
| 18 | 210th | SP Wandy Rodriguez Pit |
| 19 | 223rd | RP Matt Thornton ChA |
| 20 | 234th | 1B Brandon Belt SF |
| 21 | 247th | RP Jim Johnson Bal |
| 22 | 258th | C Jarrod Saltalamacchia Bos |
| 23 | 271st | 2B Ryan Raburn Det |
| 24 | 282nd | SP Grant Balfour Oak |
| 25 | 295th | SP Bartolo Colon Oak |
| 26 | 306th | 3B Anthony Rendon Was |
| 27 | 319th | OF Grady Sizemore Cle |
| 28 | 330th | 1B Ty Wigginton Phi |
| 29 | 343rd | SS Ruben Tejada NYN |