| Round | Overall | Player |
|---|---|---|
| 1 | 10th | 3B Evan Longoria TB |
| 2 | 15th | 1B Mark Teixeira NYA |
| 3 | 34th | 1B Eric Hosmer KC |
| 4 | 39th | OF Nelson Cruz Tex |
| 5 | 58th | 2B Rickie Weeks Mil |
| 6 | 63rd | SS Elvis Andrus Tex |
| 7 | 82nd | SP Gio Gonzalez Was |
| 8 | 87th | OF Desmond Jennings TB |
| 9 | 106th | SP Mat Latos Cin |
| 10 | 111th | OF Jason Heyward ATL |
| 11 | 130th | SP Johnny Cueto Cin |
| 12 | 135th | DH Billy Butler KC |
| 13 | 154th | SP Francisco Liriano Pit |
| 14 | 159th | SP Jair Jurrjens Atl |
| 15 | 178th | RP Carlos Marmol ChN |
| 16 | 183rd | SP Chad Billingsley LAD |
| 17 | 202nd | C J.P. Arencibia Tor |
| 18 | 207th | OF Alexis Rios ChA |
| 19 | 226th | SP Jhoulys Chacin Col |
| 20 | 231st | 3B Pedro Alvarez Pit |
| 21 | 250th | RP Matt Capps Min |
| 22 | 255th | OF Cameron Maybin SD |
| 23 | 274th | SS Cliff Pennington Oak |
| 24 | 279th | 1B Chris Davis Bal |
| 25 | 298th | 2B Jose Altuve Hou |
| 26 | 303rd | SP R.A. Dickey Tor |
| 27 | 322nd | OF Josh Reddick Oak |
| 28 | 327th | SP Gavin Floyd ChA |
| 29 | 346th | C A.J. Pierzynski Tex |