| Round | Overall | Player |
|---|---|---|
| 1 | 1st | 1B Miguel Cabrera Det |
| 2 | 24th | 2B Dustin Pedroia Bos |
| 3 | 25th | 1B Freddie Freeman Atl |
| 4 | 48th | SS Jose Reyes Tor |
| 5 | 49th | OF Matt Holliday StL |
| 6 | 72nd | 3B Josh Donaldson Oak |
| 7 | 73rd | OF Alexis Rios Tex |
| 8 | 96th | SP Matt Cain SF |
| 9 | 97th | SP Michael Wacha StL |
| 10 | 120th | SP Johnny Cueto Cin |
| 11 | 121st | RP Trevor Rosenthal StL |
| 12 | 144th | C Jason Castro Hou |
| 13 | 145th | SP Francisco Liriano Pit |
| 14 | 168th | C Matt Wieters Bal |
| 15 | 169th | OF Billy Hamilton Cin |
| 16 | 192nd | SS Xander Bogaerts Bos |
| 17 | 193rd | RP Fernando Rodney Sea |
| 18 | 216th | 3B Mike Moustakas KC |
| 19 | 217th | DH Adam Dunn ChA |
| 20 | 240th | OF Brett Gardner NYA |
| 21 | 241st | SP Bronson Arroyo Ari |
| 22 | 264th | 1B Corey Hart Sea |
| 23 | 265th | SP Bartolo Colon NYN |
| 24 | 288th | OF Dustin Ackley Sea |
| 25 | 289th | OF Jackie Bradley Bos |
| 26 | 312th | SP Scott Kazmir Oak |
| 27 | 313th | RP Nathan Jones ChA |
| 28 | 336th | SP Brandon Morrow Tor |
| 29 | 337th | SS Rafael Furcal Mia |