| Round | Overall | Player |
|---|---|---|
| 1 | 5th | SP Clayton Kershaw LAD |
| 2 | 20th | OF Adam Jones Bal |
| 3 | 29th | SP Yu Darvish Tex |
| 4 | 44th | SP Cliff Lee Phi |
| 5 | 53rd | 1B Adrian Gonzalez LAD |
| 6 | 68th | OF Hunter Pence SF |
| 7 | 77th | SP James Shields KC |
| 8 | 92nd | C Brian McCann NYA |
| 9 | 101st | SP Mat Latos Cin |
| 10 | 116th | SS Elvis Andrus Tex |
| 11 | 125th | SP Shelby Miller StL |
| 12 | 140th | OF Desmond Jennings TB |
| 13 | 149th | 3B Brett Lawrie Tor |
| 14 | 164th | 3B Chase Headley NYA |
| 15 | 173rd | RP Glen Perkins Min |
| 16 | 188th | 2B Dan Murphy NYN |
| 17 | 197th | OF Torii Hunter Det |
| 18 | 212th | RP John Axford Cle |
| 19 | 221st | SP Dan Haren LAD |
| 20 | 236th | 1B Brandon Moss Oak |
| 21 | 245th | 2B Howie Kendrick LAA |
| 22 | 260th | SP Tim Hudson SF |
| 23 | 269th | SP Michael Pineda NYA |
| 24 | 284th | C Alex Avila Det |
| 25 | 293rd | 1B Ike Davis Pit |
| 26 | 308th | SS Javier Baez ChN |
| 27 | 317th | RP Rex Brothers Col |
| 28 | 332nd | OF Andre Ethier LAD |
| 29 | 341st | RP Joakim Soria Det |