| Round | Overall | Player |
|---|---|---|
| 1 | 4th | OF Charlie Blackmon Col |
| 2 | 21st | OF George Springer Hou |
| 3 | 28th | 2B Brian Dozier LAD |
| 4 | 45th | DH Edwin Encarnacion Cle |
| 5 | 52nd | SP Yu Darvish ChN |
| 6 | 69th | DH Shohei Ohtani LAA |
| 7 | 76th | SP Aaron Nola Phi |
| 8 | 93rd | 3B Travis Shaw Mil |
| 9 | 100th | SS Jean Segura Phi |
| 10 | 117th | SP Johnny Cueto SF |
| 11 | 124th | OF Nick Castellanos Det |
| 12 | 141st | C J.T. Realmuto Mia |
| 13 | 148th | SP Luis Castillo Cin |
| 14 | 165th | OF Gregory Polanco Pit |
| 15 | 172nd | 1B Chris Davis Bal |
| 16 | 189th | SP Jeff Samardzija SF |
| 17 | 196th | RP Mark Melancon SF |
| 18 | 213th | RP Kelvin Herrera Was |
| 19 | 220th | SP Kevin Gausman Atl |
| 20 | 237th | 3B Brandon Drury Tor |
| 21 | 244th | SP Joe Musgrove Pit |
| 22 | 261st | OF Stephen Piscotty Oak |
| 23 | 268th | 1B Brad Miller Mil |
| 24 | 285th | 2B Eduardo Nunez Bos |
| 25 | 292nd | SS Ketel Marte Ari |
| 26 | 309th | C James McCann Det |
| 27 | 316th | SP Danny Salazar Cle |
| 28 | 333rd | SP Luiz Gohara Atl |
| 29 | 340th | OF Odubel Herrera Phi |