| Round | Overall | Player |
|---|---|---|
| 1 | 1st | OF Mike Trout LAA |
| 2 | 24th | SS Trevor Story Col |
| 3 | 25th | SP Chris Sale Bos |
| 4 | 48th | SS Gleyber Torres NYA |
| 5 | 49th | SP Mike Clevinger Cle |
| 6 | 72nd | OF Michael Conforto NYN |
| 7 | 73rd | 1B Dan Murphy Col |
| 8 | 96th | 3B Rafael Devers Bos |
| 9 | 97th | DH Nelson Cruz Min |
| 10 | 120th | RP Jose Leclerc Tex |
| 11 | 121st | RP Corey Knebel Mil |
| 12 | 144th | SP Eduardo Rodriguez Bos |
| 13 | 145th | OF Stephen Piscotty Oak |
| 14 | 168th | SP Jhoulys Chacin Mil |
| 15 | 169th | 2B Jonathan Schoop Min |
| 16 | 192nd | SP Jesus Luzardo Oak |
| 17 | 193rd | 1B Trey Mancini Bal |
| 18 | 216th | RP Arodys Vizcaino Atl |
| 19 | 217th | C Robinson Chirinos Hou |
| 20 | 240th | 3B Maikel Franco Phi |
| 21 | 241st | 1B C.J. Cron Min |
| 22 | 264th | SP Wade Miley Hou |
| 23 | 265th | RP A.J. Minter Atl |
| 24 | 288th | C Jorge Alfaro Mia |
| 25 | 289th | SP Kevin Gausman Atl |
| 26 | 312th | OF Corey Dickerson Pit |
| 27 | 313th | SS Dansby Swanson Atl |
| 28 | 336th | 1B Ronald Guzman Tex |
| 29 | 337th | OF Teoscar Hernández Tor |