| Round | Overall | Player |
|---|---|---|
| 1 | 1st | OF Mike Trout LAA |
| 2 | 24th | SP Jacob deGrom NYN |
| 3 | 25th | SS Trevor Story Col |
| 4 | 48th | C J.T. Realmuto Phi |
| 5 | 49th | 1B Joey Votto Cin |
| 6 | 72nd | 3B Matt Chapman Oak |
| 7 | 73rd | RP Edwin Diaz NYN |
| 8 | 96th | 2B Robinson Cano NYN |
| 9 | 97th | OF Michael Brantley Hou |
| 10 | 120th | SP Charlie Morton TB |
| 11 | 121st | OF A.J. Pollock LAD |
| 12 | 144th | RP Craig Kimbrel ChN |
| 13 | 145th | SP Yusei Kikuchi Sea |
| 14 | 168th | SP Luis Castillo Cin |
| 15 | 169th | OF Brandon Nimmo NYN |
| 16 | 192nd | SP Rich Hill LAD |
| 17 | 193rd | SP Nick Pivetta Phi |
| 18 | 216th | 1B Jake Lamb Ari |
| 19 | 217th | RP José Alvarado TB |
| 20 | 240th | OF Brett Gardner NYA |
| 21 | 241st | 1B Ryan Zimmerman Was |
| 22 | 264th | C Francisco Cervelli Pit |
| 23 | 265th | SS Amed Rosario NYN |
| 24 | 288th | 2B D.J. LeMahieu NYA |
| 25 | 289th | SP Jimmy Nelson Mil |
| 26 | 312th | SP Anibal Sanchez Was |
| 27 | 313th | 3B Todd Frazier NYN |
| 28 | 336th | OF Kyle Tucker Hou |
| 29 | 337th | 3B Kyle Seager Sea |