| Round | Overall | Player |
|---|---|---|
| 1 | 2nd | OF Mookie Betts Bos |
| 2 | 23rd | 1B Anthony Rizzo ChN |
| 3 | 26th | SP Corey Kluber Cle |
| 4 | 47th | OF Cody Bellinger LAD |
| 5 | 50th | 3B Matt Carpenter StL |
| 6 | 71st | SP Miles Mikolas StL |
| 7 | 74th | RP Kenley Jansen LAD |
| 8 | 95th | RP Brad Hand Cle |
| 9 | 98th | DH Nelson Cruz Min |
| 10 | 119th | 2B Brian Dozier Was |
| 11 | 122nd | OF Aaron Hicks NYA |
| 12 | 143rd | 2B Mike Moustakas Cin |
| 13 | 146th | SP Mike Foltynewicz Atl |
| 14 | 167th | 1B Ryan McMahon Col |
| 15 | 170th | RP Cody Allen LAA |
| 16 | 191st | SS Willy Adames TB |
| 17 | 194th | SP Aaron Sanchez Hou |
| 18 | 215th | OF Christin Stewart Det |
| 19 | 218th | SP Eric Lauer Mil |
| 20 | 239th | SS Didi Gregorius NYA |
| 21 | 242nd | SP Julio Teheran Atl |
| 22 | 263rd | 2B Jeff McNeil NYN |
| 23 | 266th | SP Kevin Gausman Atl |
| 24 | 287th | RP Dakota Hudson StL |
| 25 | 290th | SP Adam Wainwright StL |
| 26 | 311th | C Jonathan Lucroy LAA |
| 27 | 314th | SS Brandon Crawford SF |
| 28 | 335th | C Isiah Kiner-Falefa Tex |
| 29 | 338th | OF Daniel Palka ChA |