| Round | Overall | Player |
|---|---|---|
| 1 | 3rd | 3B Nolan Arenado Col |
| 2 | 22nd | SP Chris Sale Bos |
| 3 | 27th | SP Aaron Nola Phi |
| 4 | 46th | SP Walker Buehler LAD |
| 5 | 51st | OF Joey Gallo Tex |
| 6 | 70th | SP James Paxton NYA |
| 7 | 75th | OF Eloy Jimenez ChA |
| 8 | 94th | SP Germán Márquez Col |
| 9 | 99th | OF Max Kepler Min |
| 10 | 118th | RP Jose Leclerc Tex |
| 11 | 123rd | OF Stephen Piscotty Oak |
| 12 | 142nd | 3B Travis Shaw Mil |
| 13 | 147th | SP Yu Darvish ChN |
| 14 | 166th | SS Elvis Andrus Tex |
| 15 | 171st | RP David Robertson Phi |
| 16 | 190th | OF Tyler O'Neill StL |
| 17 | 195th | RP Will Smith SF |
| 18 | 214th | 3B Miguel Sano Min |
| 19 | 219th | 1B Brandon Belt SF |
| 20 | 238th | SS Lourdes Gurriel Tor |
| 21 | 243rd | C Wellington Castillo ChA |
| 22 | 262nd | 1B Trey Mancini Bal |
| 23 | 267th | 2B Garrett Hampson Col |
| 24 | 286th | 2B Jason Kipnis Cle |
| 25 | 291st | 3B Jung Ho Kang Pit |
| 26 | 310th | C Willians Astudillo Min |
| 27 | 315th | OF Carlos Gonzalez ChN |
| 28 | 334th | 1B Peter O'Brien Mia |
| 29 | 339th | SP Ervin Santana ChA |