| Round | Overall | Player |
|---|---|---|
| 1 | 5th | OF Cody Bellinger LAD |
| 2 | 20th | 3B Vladimir Guerrero Jr Tor |
| 3 | 29th | SS Xander Bogaerts Bos |
| 4 | 44th | 1B Paul Goldschmidt StL |
| 5 | 53rd | SP Aaron Nola Phi |
| 6 | 68th | 2B Gavin Lux LAD |
| 7 | 77th | OF Austin Meadows TB |
| 8 | 92nd | SP Stephen Strasburg Was |
| 9 | 101st | 1B Anthony Rizzo NYA |
| 10 | 116th | RP Edwin Diaz NYN |
| 11 | 125th | RP Raisel Iglesias LAA |
| 12 | 140th | C Will Smith LAD |
| 13 | 149th | SP Zac Gallen Ari |
| 14 | 164th | SP Germán Márquez Col |
| 15 | 173rd | OF Max Kepler Min |
| 16 | 188th | OF Kike Hernandez Bos |
| 17 | 197th | 1B Joey Votto Cin |
| 18 | 212th | 3B Justin Turner LAD |
| 19 | 221st | SP Freddy Peralta Mil |
| 20 | 236th | SP Jon Lester Was |
| 21 | 245th | RP Jordan Hicks StL |
| 22 | 260th | SS Willy Adames Mil |
| 23 | 269th | C Carson Kelly Ari |
| 24 | 284th | OF Austin Hays Bal |
| 25 | 293rd | 2B Ha-seong Kim SD |
| 26 | 308th | OF Adam Eaton ChA |
| 27 | 317th | OF Bryan Reynolds Pit |
| 28 | 332nd | RP Ian Kennedy Phi |
| 29 | 341st | SP Miles Mikolas StL |