| Round | Overall | Player |
|---|---|---|
| 1 | 3rd | OF Mookie Betts LAD |
| 2 | 22nd | SP Trevor Bauer LAD |
| 3 | 27th | 2B Ozzie Albies Atl |
| 4 | 46th | SS Javier Baez ChN |
| 5 | 51st | SP Max Fried Atl |
| 6 | 70th | 3B Yoan Moncada ChA |
| 7 | 75th | SP Tyler Glasnow TB |
| 8 | 94th | OF Franmil Reyes Cle |
| 9 | 99th | 1B C.J. Cron Col |
| 10 | 118th | OF Teoscar Hernández Tor |
| 11 | 123rd | RP James Karinchak Cle |
| 12 | 142nd | SP Chris Bassitt Oak |
| 13 | 147th | RP Jordan Romano Tor |
| 14 | 166th | OF Ian Happ ChN |
| 15 | 171st | OF Anthony Santander Bal |
| 16 | 190th | OF Kyle Schwarber Was |
| 17 | 195th | SP Elieser Hernandez Mia |
| 18 | 214th | SS Paul DeJong StL |
| 19 | 219th | 3B Nick Solak Tex |
| 20 | 238th | 1B Jesus Aguilar Mia |
| 21 | 243rd | 2B Jonathan Schoop Det |
| 22 | 262nd | RP Joakim Soria Ari |
| 23 | 267th | SP Trevor Rogers Mia |
| 24 | 286th | C Jorge Alfaro Mia |
| 25 | 291st | SP Dane Dunning Tex |
| 26 | 310th | SP Yusei Kikuchi Sea |
| 27 | 315th | OF Alex Dickerson SF |
| 28 | 334th | 3B Maikel Franco Bal |
| 29 | 339th | OF David Peralta Ari |