| Round | Overall | Player |
|---|---|---|
| 1 | 6th | OF Mookie Betts LAD |
| 2 | 19th | SS Corey Seager Tex |
| 3 | 30th | C Yasmani Grandal ChA |
| 4 | 43rd | 2B Brandon Lowe TB |
| 5 | 54th | OF Nick Castellanos Cin |
| 6 | 67th | SP Tyler Glasnow TB |
| 7 | 78th | SP Joe Musgrove SD |
| 8 | 91st | 1B Joshua Bell Cle |
| 9 | 102nd | 3B Yoan Moncada ChA |
| 10 | 115th | OF Mitch Haniger SF |
| 11 | 126th | SP Kevin Gausman Tor |
| 12 | 139th | OF Mark Canha NYN |
| 13 | 150th | 3B Eduardo Escobar NYN |
| 14 | 163rd | OF Brandon Nimmo NYN |
| 15 | 174th | SP Marcus Stroman ChN |
| 16 | 187th | OF Jorge Soler Mia |
| 17 | 198th | SP Marco Gonzales Sea |
| 18 | 211th | 2B Jean Segura Phi |
| 19 | 222nd | 3B Jeimer Candelario Det |
| 20 | 235th | 2B Nico Hoerner ChN |
| 21 | 246th | C Max Stassi LAA |
| 22 | 259th | 1B Yulieski Gurriel Hou |
| 23 | 270th | SP Kyle Hendricks ChN |
| 24 | 283rd | RP Mark Melancon Ari |
| 25 | 294th | RP Brad Hand Phi |
| 26 | 307th | SS Alcides Escobar Was |
| 27 | 318th | SP Josh Rogers Was |
| 28 | 331st | SP Spencer Turnbull Det |
| 29 | 342nd | OF LaMonte Wade Jr SF |