| Round | Overall | Player |
|---|---|---|
| 1 | 7th | 3B Jose Ramirez Cle |
| 2 | 18th | SP Walker Buehler LAD |
| 3 | 31st | SP Corbin Burnes Mil |
| 4 | 42nd | SS Fernando Tatis Jr. SD |
| 5 | 55th | SP Sandy Alcántra Mia |
| 6 | 66th | OF Joey Gallo LAD |
| 7 | 79th | SS Bobby Witt Jr. KC |
| 8 | 90th | 1B Bobby Dalbec Bos |
| 9 | 103rd | 1B Spencer Torkelson Det |
| 10 | 114th | C Yasmani Grandal ChA |
| 11 | 127th | SP Dylan Cease ChA |
| 12 | 138th | OF Hunter Renfroe Mil |
| 13 | 151st | RP Giovanny Gallegos StL |
| 14 | 162nd | 2B Jake Cronenworth SD |
| 15 | 175th | C Adley Rutschman Bal |
| 16 | 186th | SP Triston McKenzie Cle |
| 17 | 199th | 2B Keston Hiura Mil |
| 18 | 210th | SP Michael Kopech ChA |
| 19 | 223rd | 3B Patrick Wisdom ChN |
| 20 | 234th | RP Jacob McGee SF |
| 21 | 247th | SP Alexander Cobb SF |
| 22 | 258th | SS C.J. Abrams Was |
| 23 | 271st | OF Aaron Hicks NYA |
| 24 | 282nd | SP Matt Brash Sea |
| 25 | 295th | SP Tylor Megill NYN |
| 26 | 306th | 3B Jose Miranda Min |
| 27 | 319th | 1B Rowdy Tellez Mil |
| 28 | 330th | OF Mickey Moniak LAA |
| 29 | 343rd | C Eric Haase Det |