| Round | Overall | Player |
|---|---|---|
| 1 | 10th | OF Julio Rodriguez Sea |
| 2 | 15th | OF Yordan Alvarez Hou |
| 3 | 34th | RP Emmanuel Clase Cle |
| 4 | 39th | SS Corey Seager Tex |
| 5 | 58th | RP Jordan Romano Tor |
| 6 | 63rd | C J.T. Realmuto Phi |
| 7 | 82nd | RP Camilo Doval SF |
| 8 | 87th | OF Kris Bryant Col |
| 9 | 106th | SP Pablo Lopez Min |
| 10 | 111th | 1B Anthony Rizzo NYA |
| 11 | 130th | 3B Anthony Rendon LAA |
| 12 | 135th | SP Lucas Giolito LAA |
| 13 | 154th | 3B Eugenio Suarez Sea |
| 14 | 159th | 3B Ryan McMahon Col |
| 15 | 178th | OF Ian Happ ChN |
| 16 | 183rd | 1B Joshua Bell Cle |
| 17 | 202nd | SP Jonathan Gray Tex |
| 18 | 207th | 2B Jurickson Profar Col |
| 19 | 226th | 1B Josh Naylor Cle |
| 20 | 231st | SP Eduardo Rodriguez Det |
| 21 | 250th | 3B Elehuris Montero Col |
| 22 | 255th | SP Nathan Eovaldi Tex |
| 23 | 274th | SP David Peterson NYN |
| 24 | 279th | C Keibert Ruiz Was |
| 25 | 298th | SS Luis Rengifo LAA |
| 26 | 303rd | 2B Brendan Donovan StL |
| 27 | 322nd | OF Trent Grisham SD |
| 28 | 327th | SP Brayan Bello Bos |
| 29 | 346th | OF Royce Lewis Min |