| Round | Overall | Player |
|---|---|---|
| 1 | 11th | OF Mookie Betts LAD |
| 2 | 14th | OF Kyle Tucker Hou |
| 3 | 35th | SP Max Scherzer Tex |
| 4 | 38th | C Will Smith LAD |
| 5 | 59th | OF Giancarlo Stanton NYA |
| 6 | 62nd | 3B Carlos Correa Min |
| 7 | 83rd | SP Joe Musgrove SD |
| 8 | 86th | 3B Alec Bohm Phi |
| 9 | 107th | 2B Gleyber Torres NYA |
| 10 | 110th | SS Dansby Swanson ChN |
| 11 | 131st | SP Hunter Greene Cin |
| 12 | 134th | SP Dustin May LAD |
| 13 | 155th | 1B Triston Casas Bos |
| 14 | 158th | OF Riley Greene Det |
| 15 | 179th | SP Sonny Gray Min |
| 16 | 182nd | SP Jordan Montgomery Tex |
| 17 | 203rd | 3B Yoan Moncada ChA |
| 18 | 206th | C Francisco Álvarez NYN |
| 19 | 227th | SP Marcus Stroman ChN |
| 20 | 230th | SP Andrew Heaney Tex |
| 21 | 251st | OF Austin Hays Bal |
| 22 | 254th | 1B Seth Brown Oak |
| 23 | 275th | C Jonah Heim Tex |
| 24 | 278th | 2B Kolten Wong Sea |
| 25 | 299th | 1B Brandon Belt Tor |
| 26 | 302nd | SS Miguel Rojas LAD |
| 27 | 323rd | SP Justin Steele ChN |
| 28 | 326th | SP Nick Pivetta Bos |
| 29 | 347th | SP Jose Quintana NYN |