| Week | Add | Drop |
| Pre-Season |
Round 1: SP Reid Detmers - LAA Round 2: 2B Luis Rengifo - LAA Round A: OF Jung Hoo Lee - SF Round B: SS Colson Montgomery - ChA | |
| Week 1 |
Round 1: SP Brady Singer - KC Round 2: 2B Brendan Donovan - StL | |
| Week 2 |
Round 1: SP Bailey Ober - Min Round 2: 2B Vaughn Grissom - Bos |
Round 1: SP MacKenzie Gore - Was Round 2: SP Lance Lynn - StL |
| Week 4 |
Round 1: 1B Ryan O'Hearn - Bal Round 2: SS Amed Rosario - TB |
Round 1: 2B Luis Rengifo - LAA Round 2: 1B Andrew Vaughn - ChA |
| Week 6 |
Round 1: RP Tanner Scott - Mia Round 2: OF TJ Friedl - Cin |
Round 1: SS Amed Rosario - TB Round 2: SP Mitch Keller - Pit |
| Week 7 |
Round 1: SP Taijuan Walker - Phi |
| 1st Team | 2nd Team |
| Pre-Season | |
| 5 Gamers | Pollock's Cuban Stars |
|
Round 5, 8th Pick (2B Edouard Julien Min) |
SP
Dylan Cease
SD |
| Pre-Season | |
| 5 Gamers | Santa Fe Fuego |
|
SP
Walker Buehler
LAD |
Round 4, 5th Pick (2B Nico Hoerner ChN) |
| Pre-Season | |
| 5 Gamers | Chattanooga Lookouts |
|
Round 16, 4th Pick (SS Paul DeJong ChA) Round 17, 4th Pick (3B Patrick Wisdom ChN) Round 17, 7th Pick (3B Ezequiel Duran Tex) |
Round 13, 8th Pick (SP Shane McClanahan TB) |
| Pre-Season | |
| 5 Gamers | Pollock's Cuban Stars |
|
SP
Dylan Cease
SD |
C
William Contreras
Mil |
| Pre-Season | |
| 5 Gamers | Bottom of the pack 5 |
|
Round 5, 5th Pick (SS Ha-seong Kim SD) |
SS
Anthony Volpe
NYA |
| Pre-Season | |
| 5 Gamers | The Plantation |
|
2B
Thairo Estrada
SF |
Round 3, 10th Pick (3B Alec Bohm Phi) |
| Pre-Season | |
| 5 Gamers | Chattanooga Lookouts |
|
Round 18, 4th Pick (1B Matt Mervis ChN) Round 19, 4th Pick (RP Michael Kopech ChA) |
Round 5, 8th Pick (2B Edouard Julien Min) Round 11, 8th Pick (OF Lourdes Gurriel Ari) |
| Pre-Season | |
| 5 Gamers | Chattanooga Lookouts |
|
Round 9, 4th Pick (DH J.D. Martinez NYN) |
SS
Willy Adames
Mil |
| Pre-Season | |
| 5 Gamers | Pollock's Cuban Stars |
|
2B
Xander Bogaerts
SD SS Masyn Winn StL OF Evan Carter Tex Round 15, 4th Pick (RP Griffin Jax Min) |
OF
Nick Castellanos
Phi Round 1, 7th Pick (OF George Springer Tor) Round 6, 7th Pick (RP Peter Fairbanks TB) |
| Pre-Season | |
| 5 Gamers | Bottom of the pack 5 |
|
OF
Jasson Dominguez
NYA |
Round 9, 2nd Pick (1B Andrew Vaughn ChA) |
| Pre-Season | |
| 5 Gamers | Santa Fe Fuego |
|
SP
Chris Sale
Atl |
Round 5, 5th Pick (SS Ha-seong Kim SD) |
| Pre-Season | |
| 5 Gamers | Pollock's Cuban Stars |
|
Round 1, 4th Pick (OF James Wood Was) Round 6, 4th Pick (OF Parker Meadows Det) |
OF
Kyle Schwarber
Phi Round 17, 7th Pick (3B Ezequiel Duran Tex) |
| Week 7 | |
| 5 Gamers | Santa Fe Fuego |
|
2B
Vaughn Grissom
Bos |
SS
Blaze Alexander
Ari |
| Week 7 | |
| 5 Gamers | Santa Fe Fuego |
|
SP
Brady Singer
KC OF Jordan Walker StL |
RP
Josh Hader
Hou |