| Week | Add | Drop |
| Pre-Season |
Round 1: SP Seth Lugo - KC Round A: OF Jung Hoo Lee - SF Round B: SP Joe Boyle - Oak |
Round 1: SP James Paxton - LAD Round A: C Riley Adams - Was Round B: OF Dominic Canzone - Sea |
| Week 1 |
Round 1: SP Zack Littell - TB Round 2: C Elias Diaz - Col |
Round 2: SS Tim Anderson - Mia |
| Week 2 |
Round 1: SP Brady Singer - KC Round 2: SS Tyler Freeman - Cle |
Round 1: SP Bryce Elder - Atl Round 2: SP JP Sears - Oak |
| Week 3 |
Round 1: SP Tyler Anderson - LAA Round 2: OF Blake Perkins - Mil |
Round 1: SP Kyle Hendricks - ChN |
| Week 4 |
Round 1: SP Mike Lorenzen - Tex Round 2: 1B David Fry - Cle |
Round 1: 1B Kris Bryant - Col |
| Week 5 |
Round 1: 2B Rob Refsnyder - Bos Round 2: OF Trevor Larnach - Min |
Round 1: SS Geraldo Perdomo - Ari Round 2: SP Hunter Brown - Hou |
| Week 6 |
Round 1: 1B Tyler Nevin - Oak Round 2: 2B Luis Rengifo - LAA |
Round 1: 1B Ryan Noda - Oak Round 2: OF Jack Suwinski - Pit |
| Week 7 |
Round 1: OF Jonny DeLuca - TB Round 2: SP Luis Gil - NYA |
Round 1: SP Kenta Maeda - Det Round 2: 1B Tyler Nevin - Oak |
| 1st Team | 2nd Team |