| Week | Add | Drop |
| Pre-Season |
Round 2: SP DL Hall - Mil Round A: SP Shota Imanaga - ChN |
Round A: OF Luke Raley - Sea |
| Week 1 |
Round 2: RP Ronel Blanco - Hou | |
| Week 2 |
Round 1: RP Shelby Miller - Det Round 2: SP Paul Blackburn - NYN |
Round 2: SP Braxton Garrett - Mia |
| Week 3 |
Round 2: 1B LaMonte Wade Jr - SF |
Round 2: 1B Ryan Noda - Oak |
| Week 4 |
Round 1: 2B Luis Garcia - Was Round 2: RP Reed Garrett - NYN |
Round 1: 2B Brandon Drury - LAA Round 2: SP DL Hall - Mil |
| Week 5 |
Round 1: SS Tyler Freeman - Cle Round 2: OF Gavin Sheets - ChA |
Round 1: 3B Anthony Rendon - LAA Round 2: 1B LaMonte Wade Jr - SF |
| Week 6 |
Round 2: SS Cole Tucker - LAA |
Round 2: OF Chas McCormick - Hou |
| Week 7 |
Round 2: SP Spencer Turnbull - Phi |
Round 2: RP Shelby Miller - Det |
| Week 8 |
Round 1: 3B Dylan Moore - Sea Round 2: SP Bailey Falter - Pit |
Round 1: SP Jose Quintana - NYN Round 2: RP Reed Garrett - NYN |
| Week 9 |
Round 2: SP Logan Allen - Cle |
Round 2: SS Cole Tucker - LAA |
| Week 10 |
Round 1: SP Tylor Megill - NYN Round 2: SP Cody Poteet - NYA |
Round 1: SP Frankie Montas - Mil Round 2: 1B Andrew Vaughn - ChA |
| Week 11 |
Round 1: SP Adam Mazur - Mia Round 2: SS Jose Caballero - TB |
Round 1: SP Bryce Elder - Atl Round 2: RP David Bednar - Pit |
| Week 12 |
Round 1: C Travis d'Arnaud - Atl Round 2: SP Cal Quantrill - Col |
Round 1: SP Adam Mazur - Mia Round 2: SP Spencer Turnbull - Phi |
| Week 13 |
Round 1: SP Colin Rea - Mil Round 2: SP Jonathan Cannon - ChA |
Round 1: SP Aaron Civale - Mil Round 2: SP Cody Poteet - NYA |
| Week 14 |
Round 1: 1B David Fry - Cle Round 2: SP Zack Littell - TB |
Round 1: SS Jose Caballero - TB Round 2: SP Paul Blackburn - NYN |
| Week 16 |
Round 1: SP Marco Gonzales - Pit |
Round 1: SP Tylor Megill - NYN |
| Week 18 |
Round 1: SS Paul DeJong - KC Round 2: SP Tyler Phillips - Phi |
Round 1: OF Gavin Sheets - ChA Round 2: SP Bailey Falter - Pit |
| Week 19 |
Round 1: SP Michael McGreevy - StL Round 2: SP Cody Bradford - Tex |
Round 1: SP Marco Gonzales - Pit Round 2: SP Jonathan Cannon - ChA |
| Week 20 |
Round 1: SP Tyler Mahle - Tex |
Round 1: C Jonah Heim - Tex |
| 1st Team | 2nd Team |