| Week | Add | Drop |
| Pre-Season |
Round 1: SP Max Meyer - Mia |
Round 1: SP Nick Lodolo - Cin |
| Week 1 |
Round 1: RP Abner Uribe - Mil Round 2: RP Garrett Whitlock - Bos |
Round 2: RP Alex Lange - Det |
| Week 2 |
Round 1: 3B J.D. Davis - Oak |
Round 1: 3B Curtis Mead - TB |
| Week 3 |
Round 2: SP Eduardo Rodriguez - Ari |
Round 2: 2B Brendan Rodgers - Col |
| Week 4 |
Round 1: SS Amed Rosario - TB Round 2: 2B Brendan Rodgers - Col | |
| Week 5 |
Round 1: SP Graham Ashcraft - Cin Round 2: SP Kyle Gibson - StL |
Round 1: 2B Brendan Rodgers - Col Round 2: RP Abner Uribe - Mil |
| Week 6 |
Round 2: SP Colin Rea - Mil |
Round 2: SP Brandon Pfaadt - Ari |
| Week 7 |
Round 1: SP Zach Eflin - TB |
Round 1: SP Colin Rea - Mil |
| 1st Team | 2nd Team |
| Pre-Season | |
| Squeeze Play | Nashville Stars |
|
OF
Mike Trout
LAA 1B Triston Casas Bos Round 1, 6th Pick (SP Logan Gilbert Sea) Round 5, 6th Pick (SP Nathan Eovaldi Tex) |
OF
Corbin Carroll
Ari Round 18, 8th Pick (2B Brendan Rodgers Col) Round 19, 8th Pick (1B Michael Busch ChN) |
| Pre-Season | |
| Squeeze Play | Nashville Stars |
|
RP
Alexis Diaz
Cin |
Round 9, 8th Pick (SP Shota Imanaga ChN) |