| Week | Add | Drop |
| Pre-Season |
Round A: SP AJ Smith-Shawver - Atl Round B: SP Cade Horton - ChN |
Round A: OF Hunter Goodman - Col Round B: OF Sal Frelick - Mil |
| Week 1 |
Round 1: SP Brady Singer - KC Round 2: 3B Trey Lipscomb - Was | |
| Week 2 |
Round 1: 3B Josh Smith - Tex |
Round 1: 3B Elehuris Montero - Col |
| Week 3 |
Round 1: OF Heston Kjerstad - Bal |
Round 1: OF Jarred Kelenic - Atl |
| Week 4 |
Round 1: RP Mason Miller - Oak Round 2: 2B Michael Massey - KC |
Round 1: 3B Trey Lipscomb - Was |
| Week 5 |
Round 1: RP Hector Neris - ChN Round 2: C Patrick Bailey - SF |
Round 1: SP Jesus Luzardo - Mia Round 2: OF Jack Suwinski - Pit |
| Week 6 |
Round 1: 2B Brandon Lowe - TB |
Round 1: C Henry Davis - Pit |
| 1st Team | 2nd Team |
| Pre-Season | |
| Horseheads Buffalos | Louisville Bats |
|
1B
Triston Casas
Bos 3B Noelvi Marte Cin SS Ezequiel Tovar Col SS Jordan Lawlar Ari Round 2, 11th Pick (SP Gavin Williams Cle) |
SP
Gerrit Cole
NYA |
| Pre-Season | |
| Horseheads Buffalos | Whiz Kids |
|
Round 4, 3rd Pick (SP Shane Bieber Cle) |
Round 2, 11th Pick (SP Gavin Williams Cle) Round 7, 11th Pick (SP Kyle Harrison SF) |
| Pre-Season | |
| Horseheads Buffalos | The Shogun of Harlem |
|
C
Endy Rodriguez
Pit |
Round 7, 8th Pick (SP Bailey Ober Min) |