| Week | Add | Drop |
| Pre-Season |
Round 1: SP Ryne Nelson - Ari Round 2: 3B Elehuris Montero - Col Round A: C Ethan Salas - SD |
Round A: C Patrick Bailey - SF |
| Week 1 |
Round 2: OF Starling Marte - NYN | |
| Week 2 |
Round 1: SP Kyle Gibson - StL Round 2: C Patrick Bailey - SF | |
| Week 3 |
Round 1: SP Matt Manning - Det Round 2: SS Gavin Lux - LAD | |
| Week 4 |
Round 1: RP Kirby Yates - Tex | |
| Week 5 |
Round 1: OF Hunter Goodman - Col Round 2: OF Jo Adell - LAA |
Round 1: OF Aaron Hicks - LAA Round 2: C Alejandro Kirk - Tor |
| Week 6 |
Round 1: 2B Willi Castro - Min Round 2: 3B Bryan Ramos - ChA |
Round 1: OF Mickey Moniak - LAA Round 2: OF Sal Frelick - Mil |
| Week 7 |
Round 1: OF Mike Tauchman - ChN Round 2: C Gary Sanchez - Mil |
Round 1: SP Shane Bieber - Cle Round 2: SP Matt Manning - Det |
| 1st Team | 2nd Team |
| Pre-Season | |
| Enid Harvesters | Mo Money Mo Problems |
|
Round 3, 5th Pick (RP Alexis Diaz Cin) Round 6, 5th Pick (1B Andrew Vaughn ChA) |
1B
Anthony Rizzo
NYA OF Josh Lowe TB |
| Pre-Season | |
| Enid Harvesters | Broken Hallelujah |
|
Round 1, 5th Pick (OF Nick Castellanos Phi) Round 10, 5th Pick (C Willson Contreras StL) |
1B
Paul Goldschmidt
StL |
| Week 7 | |
| Enid Harvesters | The Shogun of Harlem |
|
1B
Rhys Hoskins
Mil OF Randy Arozarena TB |
OF
Jordan Walker
StL 1B Christian Encarnacion-Strand Cin |