| Week | Add | Drop |
| Pre-Season |
Round 1: OF Mitch Haniger - Sea Round 2: 1B Rowdy Tellez - Pit | |
| Week 2 |
Round 1: OF Micahel Taylor - Pit | |
| Week 3 |
Round 1: OF James Outman - LAD Round 2: SS Gavin Lux - LAD |
Round 1: SP Kyle Hendricks - ChN |
| Week 4 |
Round 1: OF Andy Pages - LAD |
Round 1: OF Micahel Taylor - Pit |
| Week 5 |
Round 1: OF Wilyer Abreu - Bos Round 2: OF Jo Adell - LAA |
Round 2: OF Parker Meadows - Det Round 2: SP Graham Ashcraft - Cin |
| Week 6 |
Round 1: OF Jordan Beck - Col Round 2: OF Max Kepler - Min |
Round 2: RP Griffin Jax - Min |
| Week 7 |
Round 1: OF Jonny DeLuca - TB Round 2: C Gary Sanchez - Mil |
Round 1: OF Jack Suwinski - Pit Round 2: OF James Outman - LAD Round 2: SS Gavin Lux - LAD Round 2: 1B Rowdy Tellez - Pit |
| 1st Team | 2nd Team |
| Pre-Season | |
| San Diego Tigers | Ft Myers Bull Sharks |
|
Round 2, 1st Pick (SP Chris Sale Atl) |
SP
Drew Smyly
ChN |
| Week 6 | |
| San Diego Tigers | Bleacher Bums |
|
SP
Luis Castillo
Sea OF Lars Nootbaar StL |
SS
Gabriel Arias
Cle OF Jarren Duran Bos |
| Week 7 | |
| San Diego Tigers | Mo Money Mo Problems |
|
C
Luis Campusano
SD |
OF
Joey Loperfido
Hou |