| Week | Add | Drop |
| Pre-Season |
Round 1: SP Luis Gil - NYA Round A: OF Jung Hoo Lee - SF Round B: RP Ryan Helsley - StL Round C: 2B Brendan Rodgers - Col Round D: OF Spencer Jones - NYA |
Round A: SS Osleivis Basabe - TB Round B: SP Andrew Abbott - Cin |
| Week 1 |
Round 1: 2B Cavan Biggio - Atl Round 2: SP Tyler Wells - Bal |
Round 2: SP Bailey Ober - Min |
| Week 2 |
Round 1: RP Ronel Blanco - Hou Round 2: SS David Hamilton - Bos |
Round 1: 1B Jose Abreu - Hou Round 2: 2B Cavan Biggio - Atl |
| Week 3 |
Round 1: SP Christian Scott - NYN Round 2: 2B Jace Jung - Det |
Round 1: SP Tyler Wells - Bal |
| Week 4 |
Round 1: 3B Orelvis Martinez - Tor Round 2: SP AJ Smith-Shawver - Atl |
Round 2: SP Gavin Stone - LAD |
| Week 5 |
Round 1: OF Trevor Larnach - Min Round 2: RP Yennier Cano - Bal |
Round 1: SP AJ Smith-Shawver - Atl Round 2: SS Colson Montgomery - ChA |
| Week 6 |
Round 1: SP Cade Horton - ChN Round 2: SP Mason Black - SF |
Round 1: RP Yennier Cano - Bal Round 2: OF James Outman - LAD |
| Week 7 |
Round 1: 2B Nick Gonzales - Pit Round 2: OF Wenceel Perez - Det |
Round 1: SP Mason Black - SF Round 2: OF Jung Hoo Lee - SF Round 2: SP Cade Horton - ChN |
| Week 8 |
Round 1: 2B Michael Massey - KC Round 2: SS Marco Luciano - SF |
Round 1: SS David Hamilton - Bos Round 2: OF MJ Melendez - KC |
| Week 9 |
Round 1: SP Cade Povich - Bal Round 1: SP Cade Povich - Bal Round 2: SS David Hamilton - Bos |
Round 1: C Austin Wells - NYA Round 1: C Austin Wells - NYA Round 2: 2B Michael Massey - KC |
| Week 10 |
Round 1: 1B Kris Bryant - Col Round 2: C Henry Davis - Pit |
Round 2: SS Marco Luciano - SF |
| Week 11 |
Round 1: SP Max Meyer - Mia Round 2: SS Adael Amador - Col |
Round 1: 1B Kris Bryant - Col Round 2: OF Spencer Jones - NYA |
| Week 12 |
Round 1: SP Shane Baz - TB Round 2: 1B Spencer Horwitz - Tor |
Round 1: C Henry Davis - Pit Round 2: SS Adael Amador - Col Round 2: SP Jackson Jobe - Det Round 2: SP Cade Povich - Bal |
| Week 13 |
Round 1: SP Yu Darvish - SD Round 2: SS Marcelo Mayer - Bos | |
| Week 14 |
Round 1: OF Cedric Mullins - Bal Round 2: C Samuel Basallo - Bal |
Round 1: 3B Orelvis Martinez - Tor Round 2: C Luis Campusano - SD |
| Week 15 |
Round 1: OF Spencer Jones - NYA Round 2: SP Jackson Jobe - Det |
Round 1: OF Wenceel Perez - Det Round 2: SP Yu Darvish - SD |
| Week 16 |
Round 1: SP Chase Burns - Cin Round 2: OF Jo Adell - LAA |
Round 1: SS Marcelo Mayer - Bos Round 2: SP Carlos Rodon - NYA |
| Week 17 |
Round 2: OF Trevor Larnach - Min | |
| Week 18 |
Round 1: SP River Ryan - LAD Round 2: C Austin Wells - NYA |
Round 2: 2B Nick Gonzales - Pit |
| Week 19 |
Round 1: SP Hayden Birdsong - SF Round 2: OF Walker Jenkins - Min |
Round 1: SP Christian Scott - NYN Round 2: SP Gavin Williams - Cle |
| Week 20 |
Round 1: SS Seaver King - Was Round 2: RP Ryan Walker - SF |
Round 1: SP Hayden Birdsong - SF Round 2: SP River Ryan - LAD |
| Week 22 |
Round 2: SS David Hamilton - Bos |
| 1st Team | 2nd Team |
| Pre-Season | |
| Giants | “1969” |
|
SP
Paul Skenes
Pit |
Round 4, 4th Pick (SP Gavin Williams Cle) |
| Pre-Season | |
| Giants | Bleacher Bums |
|
Round 5, 10th Pick (RP Peter Fairbanks TB) |
RP
Edwin Diaz
NYN |
| Pre-Season | |
| Giants | Glendale Desert Dogs |
|
OF
Mike Trout
LAA Round 18, 10th Pick (C Freddy Fermin KC) Round 19, 10th Pick (SP Tanner Houck Bos) |
Round 2, 2nd Pick (SP Carlos Rodon NYA) Round 1, 8th Pick (SP Chris Sale Atl) Round 4, 11th Pick (SP Kyle Harrison SF) |