| Week | Add | Drop |
| Pre-Season |
Round 1: SS Gavin Lux - LAD Round 2: RP James McArthur - KC Round A: OF Jung Hoo Lee - SF Round B: RP Ryan Helsley - StL Round C: 3B Anthony Rendon - LAA |
Round A: RP David Robertson - Tex Round B: SP Emerson Hancock - Sea |
| Week 1 |
Round 1: RP Garrett Whitlock - Bos Round 2: 3B Ezequiel Duran - Tex | |
| Week 2 |
Round 1: OF Heston Kjerstad - Bal Round 2: SS David Hamilton - Bos |
Round 2: OF Daulton Varsho - Tor |
| Week 3 |
Round 1: SP Christian Scott - NYN Round 2: 2B Jace Jung - Det |
Round 1: SS Gavin Lux - LAD Round 2: 3B Ezequiel Duran - Tex |
| Week 4 |
Round 1: 2B Michael Massey - KC Round 2: SP AJ Smith-Shawver - Atl |
Round 1: C Austin Wells - NYA Round 2: 1B Nolan Schanuel - LAA |
| Week 5 |
Round 1: OF Pete Crow-Armstrong - ChN Round 2: RP Yennier Cano - Bal |
Round 1: SS David Hamilton - Bos Round 2: SS Colson Montgomery - ChA |
| Week 6 |
Round 1: SP Cade Horton - ChN Round 2: SP Mason Black - SF |
Round 1: RP Yennier Cano - Bal Round 2: C Henry Davis - Pit |
| Week 7 |
Round 1: SP Robert Gasser - Mil Round 2: OF Wenceel Perez - Det |
Round 1: RP Garrett Whitlock - Bos Round 2: OF Jung Hoo Lee - SF |
| Week 8 |
Round 1: SP Jesus Luzardo - Mia Round 2: OF Luis Matos - SF |
Round 1: SP Mason Black - SF Round 2: OF Heston Kjerstad - Bal |
| Week 9 |
Round 1: SP Cade Povich - Bal Round 2: 3B D.J. LeMahieu - NYA |
Round 1: SP AJ Smith-Shawver - Atl Round 2: 2B Michael Massey - KC |
| Week 10 |
Round 1: RP Reed Garrett - NYN Round 2: C Henry Davis - Pit |
Round 1: SP Cade Horton - ChN Round 2: OF MJ Melendez - KC |
| Week 11 |
Round 1: 3B Justyn-Henry Malloy - Det Round 2: SS Adael Amador - Col |
Round 1: OF Luis Matos - SF Round 2: RP Reed Garrett - NYN |
| Week 12 |
Round 1: SP Nestor Cortes Jr. - NYA Round 2: 1B Spencer Horwitz - Tor |
Round 1: SP Robert Gasser - Mil Round 2: SP Jackson Jobe - Det |
| Week 13 |
Round 1: SS Brooks Lee - Min Round 2: SP Jackson Jobe - Det |
Round 1: SS Adael Amador - Col Round 2: SP Jesus Luzardo - Mia |
| Week 14 |
Round 1: C Samuel Basallo - Bal Round 2: SS Marcelo Mayer - Bos |
Round 1: C Henry Davis - Pit Round 2: C Bo Naylor - Cle |
| Week 15 |
Round 1: SS Jacob Wilson - Oak Round 2: OF Matt Wallner - Min |
Round 1: 3B D.J. LeMahieu - NYA Round 2: 3B Justyn-Henry Malloy - Det |
| Week 16 |
Round 1: 2B Travis Bazzana - Cle Round 2: OF Lawrence Butler - Oak |
Round 1: SS Marcelo Mayer - Bos Round 2: SP Cade Povich - Bal |
| Week 18 |
Round 1: SP River Ryan - LAD Round 2: OF Tommy Pham - KC |
Round 1: SP Christian Scott - NYN Round 2: SS Jacob Wilson - Oak |
| Week 19 |
Round 1: SP Paul Blackburn - NYN |
Round 1: OF Tommy Pham - KC Round 2: OF Wenceel Perez - Det |
| Week 20 |
Round 1: RP Kenley Jansen - Bos Round 2: RP Ryan Walker - SF |
Round 1: SP Nestor Cortes Jr. - NYA Round 2: RP James McArthur - KC |
| 1st Team | 2nd Team |
| Pre-Season | |
| Marlins | Michigan Maulers 1 |
|
SP
Zach Eflin
Bal |
Round 8, 5th Pick (C Henry Davis Pit) |
| Pre-Season | |
| Marlins | Mo Money Mo Problems |
|
Round 2, 8th Pick (SP Brayan Bello Bos) |
3B
Royce Lewis
Min |
| Pre-Season | |
| Marlins | Lansing Lugnuts |
|
2B
Zack Gelof
Oak |
Round 6, 3rd Pick (RP Craig Kimbrel Bal) |
| Pre-Season | |
| Marlins | Michigan Maulers 1 |
|
2B
Matt McLain
Cin Round 17, 8th Pick (2B Luis Rengifo LAA) Round 18, 8th Pick (OF Steven Kwan Cle) Round 19, 8th Pick |
Round 2, 1st Pick (SP Chris Sale Atl) Round 2, 5th Pick (SP Carlos Rodon NYA) |
| Pre-Season | |
| Marlins | Michigan Maulers 1 |
|
1B
Nate Lowe
Tex Round 6, 3rd Pick (RP Craig Kimbrel Bal) |
RP
Edwin Diaz
NYN |