| Week | Add | Drop |
| Week 2 |
Round 1: SP Sean Manaea - NYN Round 2: SP Spencer Turnbull - Phi |
Round 1: 1B Kris Bryant - Col |
| Week 3 |
Round 1: SP Colin Rea - Mil Round 2: OF Brandon Marsh - Phi |
Round 1: SP Shane Bieber - Cle |
| Week 4 |
Round 1: SP Yusei Kikuchi - Tor Round 2: 1B Ryan O'Hearn - Bal |
Round 2: 1B Joey Meneses - Was |
| Week 5 |
Round 1: RP Hector Neris - ChN |
Round 1: SP John Means - Bal |
| Week 6 |
Round 1: SP Hayden Wesneski - ChN Round 2: 3B Nick Senzel - Was |
Round 1: RP David Robertson - Tex Round 2: OF Nelson Velazquez - KC |
| Week 7 |
Round 1: OF Ryan McKenna - Bal Round 2: SP Alek Manoah - Tor |
Round 1: SP Spencer Turnbull - Phi Round 2: 3B Nick Senzel - Was |
| 1st Team | 2nd Team |
| Week 4 | |
| My Way | Montreal Expos |
|
3B
Alec Bohm
Phi 1B Vinnie Pasquantino KC |
OF
Jarren Duran
Bos RP Ronel Blanco Hou |
| Week 8 | |
| My Way | The Abusement Park |
|
SS
Jeremy Pena
Hou OF Seiya Suzuki ChN |
2B
Gleyber Torres
NYA OF Spencer Steer Cin |