| Week | Add | Drop |
| Pre-Season |
Round 1: RP Michael Kopech - LAD Round 2: SP Reese Olson - Det Round A: SP Shane Baz - TB Round B: SP Trevor Bauer - LAD |
Round A: OF Tommy Edman - LAD Round B: 3B Andruw Monasterio - Mil |
| Week 1 |
Round 1: SP Sean Manaea - NYN Round 2: 1B Jared Walsh - ChA |
Round 2: 1B Joey Meneses - Was |
| Week 2 |
Round 1: OF Joey Gallo - Was Round 2: 2B Luis Garcia - Was |
Round 1: OF Max Kepler - Min Round 2: OF Joey Gallo - Was |
| Week 3 |
Round 1: OF Brandon Marsh - Phi |
Round 1: 3B Yoan Moncada - ChA |
| Week 4 |
Round 1: OF Jesse Winker - NYN |
Round 1: OF Jarred Kelenic - Atl |
| Week 5 |
Round 2: 2B Willi Castro - Min |
Round 2: RP Adbert Alzolay - ChN |
| Week 6 |
Round 1: OF Brent Rooker - Oak Round 2: 1B Nolan Schanuel - LAA |
Round 1: RP Michael Kopech - LAD Round 2: 1B Jared Walsh - ChA |
| Week 7 |
Round 1: SP Chris Paddack - Min Round 2: C Gary Sanchez - Mil |
Round 1: OF Brandon Marsh - Phi Round 2: OF Jesse Winker - NYN |
| Week 8 |
Round 1: OF Willie Calhoun - LAA Round 2: SS Marco Luciano - SF |
Round 1: SP Chris Paddack - Min Round 2: C Henry Davis - Pit |
| Week 9 |
Round 2: SP Chris Paddack - Min |
Round 2: OF Willie Calhoun - LAA |
| Week 10 |
Round 1: 2B Brendan Rodgers - Col |
Round 1: SS Marco Luciano - SF |
| Week 11 |
Round 1: RP Yimi Garcia - Sea Round 2: 1B Ty France - Cin |
Round 1: SP Chris Paddack - Min Round 2: OF Lars Nootbaar - StL |
| Week 12 |
Round 1: SP Chris Paddack - Min |
Round 1: 2B Brendan Rodgers - Col |
| Week 13 |
Round 1: SP David Peterson - NYN Round 2: SP Landon Knack - LAD |
Round 1: RP Yimi Garcia - Sea Round 2: 1B Ty France - Cin |
| Week 14 |
Round 2: OF Hunter Goodman - Col |
Round 2: SP Chris Paddack - Min |
| Week 15 |
Round 1: C Gabriel Moreno - Ari Round 2: RP Jeff Hoffman - Phi |
Round 1: OF Hunter Goodman - Col Round 2: SP Landon Knack - LAD |
| Week 16 |
Round 1: SP Ryan Pepiot - TB Round 2: OF Charlie Blackmon - Col |
Round 1: C Gary Sanchez - Mil Round 2: SP Dustin May - LAD |
| Week 18 |
Round 1: RP Daniel Hudson - LAD Round 2: SS Gavin Lux - LAD |
Round 1: OF Charlie Blackmon - Col Round 2: SP Ryan Pepiot - TB |
| Week 19 |
Round 1: SP Hayden Birdsong - SF Round 2: RP Chad Green - Tor |
Round 1: SP Triston McKenzie - Cle Round 2: RP Daniel Hudson - LAD |
| Week 20 |
Round 1: C Joey Bart - Pit Round 2: SP Ryne Nelson - Ari |
Round 1: C Gabriel Moreno - Ari Round 2: RP Jeff Hoffman - Phi |
| Week 22 |
Round 1: RP Michael Kopech - LAD Round 2: RP Justin Martinez - Ari |
Round 1: 2B Nolan Gorman - StL Round 2: SP Hayden Birdsong - SF |
| 1st Team | 2nd Team |
| Pre-Season | |
| Wait Til This Year | Salt River Rafters |
|
OF
Christian Yelich
Mil 1B Christian Encarnacion-Strand Cin |
Round 2, 10th Pick (OF Teoscar Hernández LAD) Round 5, 10th Pick (SP Justin Verlander Hou) |