| Week | Add | Drop |
| Pre-Season |
Round 1: SP Luis Gil - NYA Round A: RP Edwin Diaz - NYN Round B: OF Spencer Jones - NYA Round C: SS Gavin Lux - LAD Round D: SS Zach Neto - LAA |
Round 1: SP Gavin Williams - Cle Round A: SS Osleivis Basabe - TB Round B: SP Andrew Abbott - Cin |
| Week 1 |
Round 1: RP Jason Foley - Det Round 2: RP Griffin Jax - Min |
Round 2: SP Bailey Ober - Min |
| Week 2 |
Round 1: 1B Joey Meneses - Was Round 2: RP James McArthur - KC |
Round 1: RP Griffin Jax - Min Round 2: OF Daulton Varsho - Tor |
| Week 3 |
Round 1: SP Christian Scott - NYN Round 2: 2B Jace Jung - Det |
Round 1: C Austin Wells - NYA |
| Week 4 |
Round 1: 3B Orelvis Martinez - Tor Round 2: C Miguel Amaya - ChN |
Round 1: 1B Nolan Schanuel - LAA |
| Week 5 |
Round 1: OF Trevor Larnach - Min Round 2: RP Yennier Cano - Bal |
Round 1: SP Frankie Montas - Mil Round 2: OF Spencer Jones - NYA |
| Week 6 |
Round 1: SP Cade Horton - ChN Round 2: SP Mason Black - SF |
Round 1: RP Yennier Cano - Bal Round 2: 1B Joey Meneses - Was |
| Week 7 |
Round 1: 2B Nick Gonzales - Pit Round 2: OF Charlie Blackmon - Col |
Round 1: SP Mason Black - SF Round 2: OF Jung Hoo Lee - SF |
| Week 8 |
Round 1: OF Luis Matos - SF Round 2: 2B Xander Bogaerts - SD |
Round 1: SP Cade Horton - ChN Round 2: OF MJ Melendez - KC |
| Week 9 |
Round 1: 1B Jonathan Singleton - Hou Round 1: 1B Jonathan Singleton - Hou |
Round 1: 2B Xander Bogaerts - SD Round 1: 2B Xander Bogaerts - SD |
| Week 10 |
Round 1: 1B Kris Bryant - Col Round 2: C Henry Davis - Pit |
Round 1: 1B Jonathan Singleton - Hou Round 2: C Miguel Amaya - ChN |
| Week 11 |
Round 1: 3B Justyn-Henry Malloy - Det Round 2: OF Jesse Winker - NYN |
Round 1: OF Luis Matos - SF Round 2: 1B Kris Bryant - Col |
| Week 12 |
Round 1: 1B Spencer Horwitz - Tor Round 2: SP David Festa - Min |
Round 1: RP Jason Foley - Det Round 2: C Henry Davis - Pit Round 2: SP Jackson Jobe - Det |
| Week 13 |
Round 1: SP Max Meyer - Mia Round 2: SP Jackson Jobe - Det |
Round 1: OF Charlie Blackmon - Col Round 2: 3B Orelvis Martinez - Tor Round 2: SP Casey Mize - Det |
| Week 14 |
Round 1: OF Luis Matos - SF Round 2: OF Jo Adell - LAA |
Round 2: SP David Festa - Min Round 2: 3B Justyn-Henry Malloy - Det |
| Week 15 |
Round 1: SS Jacob Wilson - Oak Round 2: OF Parker Meadows - Det |
Round 1: OF Luis Matos - SF |
| Week 16 |
Round 1: 2B Travis Bazzana - Cle Round 2: OF Charlie Condon - Col |
Round 2: SP Carlos Rodon - NYA |
| Week 18 |
Round 1: OF Tyler Fitzgerald - SF Round 2: SP River Ryan - LAD |
Round 1: SP Christian Scott - NYN Round 2: 2B Nick Gonzales - Pit |
| Week 19 |
Round 1: C Austin Wells - NYA Round 2: OF Matt Wallner - Min |
Round 1: OF Trevor Larnach - Min Round 2: OF Jo Adell - LAA |
| Week 20 |
Round 1: SP David Festa - Min Round 2: RP Ryan Walker - SF |
Round 1: RP James McArthur - KC Round 2: SP River Ryan - LAD |
| 1st Team | 2nd Team |
| Pre-Season | |
| This One's for Trader Joe!!! | South Beach Boys |
|
C
Sean Murphy
Atl |
Round 3, 5th Pick (2B Colt Keith Det) |
| Pre-Season | |
| This One's for Trader Joe!!! | Arkansas Travelers |
|
OF
Mike Trout
LAA |
Round 1, 8th Pick (OF Dylan Crews Was) Round 2, 8th Pick (C Francisco Álvarez NYN) Round 4, 8th Pick (OF Jung Hoo Lee SF) |
| Pre-Season | |
| This One's for Trader Joe!!! | Chicago Dogs |
|
OF
Nick Castellanos
Phi Round 19, 12th Pick (SP Jared Jones Pit) |
Round 8, 9th Pick (C Austin Wells NYA) |