| Week | Add | Drop |
| Pre-Season |
Round 1: RP Kevin Ginkel - Ari Round 2: SS Brayan Rocchio - Cle | |
| Week 1 |
Round 1: 2B Brice Turang - Mil Round 2: OF Micahel Taylor - Pit |
Round 2: RP Paul Sewald - Ari |
| Week 2 |
Round 1: RP José Alvarado - Phi |
Round 1: RP Kevin Ginkel - Ari |
| Week 3 |
Round 1: OF Joey Loperfido - Hou Round 2: 2B Willi Castro - Min |
Round 1: 3B Yoan Moncada - ChA Round 2: RP José Alvarado - Phi |
| Week 4 |
Round 1: RP Kirby Yates - Tex Round 2: 1B Joshua Bell - Mia |
Round 1: SP Frankie Montas - Cin Round 2: SS Brayan Rocchio - Cle |
| Week 5 |
Round 1: C Travis d'Arnaud - Atl Round 2: 3B Nick Senzel - Was |
Round 1: OF Micahel Taylor - Pit Round 2: SP Triston McKenzie - Cle |
| Week 6 |
Round 1: SP Christian Scott - NYN Round 2: OF Tommy Pham - ChA |
Round 1: OF Jarred Kelenic - Atl Round 2: SP Max Scherzer - Tex |
| Week 7 |
Round 1: OF Max Kepler - Min |
Round 1: OF Will Benson - Cin |
| 1st Team | 2nd Team |
| Pre-Season | |
| Fightin Phils | New York City MSG |
|
Round 11, 5th Pick (3B Maikel Garcia KC) Round 12, 5th Pick (SP Nick Lodolo Cin) Round 16, 5th Pick (SP Clarke Schmidt NYA) |
Round 9, 11th Pick (3B Yoan Moncada ChA) |
| Pre-Season | |
| Fightin Phils | Poker in the Rear |
|
OF
Mike Trout
LAA |
2B
Matt McLain
Cin |
| Pre-Season | |
| Fightin Phils | Poker in the Rear |
|
Round 13, 5th Pick (1B Kris Bryant Col) Round 14, 5th Pick (1B Ty France Sea) Round 18, 5th Pick (SP Zack Littell TB) Round 19, 5th Pick (3B Elehuris Montero Col) |
Round 11, 9th Pick (SP Cristopher Sanchez Phi) |
| Pre-Season | |
| Fightin Phils | New York City MSG |
|
OF
James Wood
Was Round 11, 9th Pick (SP Cristopher Sanchez Phi) |
Round 7, 11th Pick (C Jonah Heim Tex) |
| Pre-Season | |
| Fightin Phils | Poker in the Rear |
|
SP
Aaron Nola
Phi |
Round 7, 9th Pick (RP Ryan Helsley StL) |
| Pre-Season | |
| Fightin Phils | Buffalo Horseheads |
|
Round 17, 5th Pick (SP Reese Olson Det) |
Round 6, 8th Pick (DH J.D. Martinez NYN) |
| Pre-Season | |
| Fightin Phils | New York City MSG |
|
Round 15, 5th Pick (SS Geraldo Perdomo Ari) |
Round 6, 11th Pick (OF Jarred Kelenic Atl) |
| Pre-Season | |
| Fightin Phils | Poker in the Rear |
|
C
Endy Rodriguez
Pit |
Round 2, 9th Pick (RP Paul Sewald Ari) Round 5, 9th Pick (1B Andrew Vaughn ChA) Round 6, 9th Pick (SP Bryce Miller Sea) Round 8, 9th Pick (2B Andrés Gimenez Cle) |
| Pre-Season | |
| Fightin Phils | New York City MSG |
|
OF
Josh Lowe
TB |
SP
Aaron Nola
Phi |
| Week 6 | |
| Fightin Phils | Poker in the Rear |
|
C
Francisco Álvarez
NYN OF Chase DeLauter Cle |
OF
Will Benson
Cin SS Blaze Alexander Ari |
| Week 6 | |
| Fightin Phils | Vanilla Gorillas |
|
SP
Walker Buehler
LAD |
1B
Jeimer Candelario
Cin SP Jordan Montgomery Ari |