| Week | Add | Drop |
| Pre-Season |
Round 1: OF Charlie Blackmon - Col Round 2: 2B Brendan Donovan - StL Round A: SP Jacob deGrom - Tex Round B: 1B Jose Abreu - Hou Round C: OF Spencer Jones - NYA Round D: OF Will Benson - Cin | |
| Week 1 |
Round 1: OF Starling Marte - NYN Round 2: 3B Trey Lipscomb - Was | |
| Week 2 |
Round 1: OF Joey Gallo - Was Round 2: 2B Luis Garcia - Was |
Round 1: OF TJ Friedl - Cin Round 2: SP Kyle Freeland - Col |
| Week 3 |
Round 1: SP Dean Kremer - Bal Round 2: SP Kenta Maeda - Det |
Round 1: 3B Trey Lipscomb - Was Round 2: OF Joey Gallo - Was |
| Week 4 |
Round 1: OF Wilyer Abreu - Bos Round 2: 3B Patrick Wisdom - ChN |
Round 2: SP Kenta Maeda - Det |
| Week 5 |
Round 1: OF Blake Perkins - Mil Round 2: 3B Nick Senzel - Was |
Round 1: 3B Anthony Rendon - LAA Round 2: OF Garrett Mitchell - Mil |
| Week 6 |
Round 1: OF Tommy Pham - ChA Round 2: OF Richie Palacios - TB |
Round 1: 3B Patrick Wisdom - ChN |
| 1st Team | 2nd Team |
| Pre-Season | |
| Red Dragon | The Halle-Day Saints |
|
3B
Max Muncy
LAD Round 3, 12th Pick (SP Sonny Gray StL) |
3B
Nolan Arenado
StL Round 15, 9th Pick (C Ryan Jeffers Min) |
| Pre-Season | |
| Red Dragon | Altoona Curve |
|
SP
Chris Sale
Atl |
Round 7, 11th Pick (RP Kenley Jansen Bos) |
| Pre-Season | |
| Red Dragon | Altoona Curve |
|
SP
Justin Verlander
Hou |
Round 6, 7th Pick (OF Giancarlo Stanton NYA) |
| Pre-Season | |
| Red Dragon | Altoona Curve |
|
Round 10, 12th Pick (OF Ceddanne Rafaela Bos) |
C
Bo Naylor
Cle |
| Pre-Season | |
| Red Dragon | Mesa Solar Sox |
|
3B
Noelvi Marte
Cin |
Round 5, 2nd Pick (SP Triston McKenzie Cle) |
| Pre-Season | |
| Red Dragon | First Degree Burnes |
|
RP
Jordan Romano
Tor Round 12, 12th Pick (OF Steven Kwan Cle) |
Round 3, 7th Pick (RP Clay Holmes NYA) |
| Pre-Season | |
| Red Dragon | Mesa Solar Sox |
|
Round 4, 12th Pick (2B Jordan Westburg Bal) |
OF
Spencer Steer
Cin |
| Week 2 | |
| Red Dragon | Cardinals |
|
2B
Brendan Donovan
StL |
SP
Kyle Gibson
StL |
| Week 2 | |
| Red Dragon | Altoona Curve |
|
OF
Nick Castellanos
Phi |
SP
Logan Allen
Cle |
| Week 4 | |
| Red Dragon | Altoona Curve |
|
RP
Kenley Jansen
Bos OF Chase DeLauter Cle |
RP
Evan Phillips
LAD |
| Week 4 | |
| Red Dragon | Mr Baseball Bob Uecker |
|
OF
Starling Marte
NYN |
SP
Blake Snell
SF |
| Week 5 | |
| Red Dragon | Altoona Curve |
|
SP
Triston McKenzie
Cle |
1B
Nate Lowe
Tex |
| Week 6 | |
| Red Dragon | Chaos Creators |
|
OF
Wilyer Abreu
Bos SP Logan Allen Cle |
SP
Chris Bassitt
Tor |