| Week | Add | Drop |
| Pre-Season |
Round 1: C Ryan Jeffers - Min Round 2: OF Mitch Haniger - Sea Round A: 2B Vaughn Grissom - Bos Round B: SP Michael King - SD Round C: 1B Kris Bryant - Col Round D: SP Andrew Abbott - Cin |
Round A: C Riley Adams - Was Round B: 3B Carter Kieboom - Was Round C: OF Mike Tauchman - ChN |
| Week 1 |
Round 1: RP Garrett Whitlock - Bos Round 2: SS Gavin Lux - LAD | |
| Week 2 |
Round 1: OF Heston Kjerstad - Bal Round 2: SP Bailey Ober - Min |
Round 1: SS Gavin Lux - LAD Round 2: SP Louie Varland - Min |
| Week 3 |
Round 1: SP Reynaldo Lopez - Atl Round 2: SP Edward Cabrera - Mia |
Round 1: SP Shane Baz - TB Round 2: 3B J.D. Davis - Oak |
| Week 4 |
Round 1: OF Daulton Varsho - Tor Round 2: SS Amed Rosario - TB |
Round 1: RP Garrett Whitlock - Bos Round 2: SS Zach Neto - LAA |
| Week 5 |
Round 1: SS Zach Neto - LAA Round 2: 3B Jose Miranda - Min |
Round 1: SS Amed Rosario - TB Round 2: OF Heston Kjerstad - Bal |
| Week 6 |
Round 1: 2B Luis Rengifo - LAA Round 2: SP Shane Baz - TB |
Round 1: 3B Jose Miranda - Min Round 2: OF Mitch Haniger - Sea |
| Week 7 |
Round 1: SP Jesus Luzardo - Mia Round 2: 3B Nick Senzel - Was |
Round 1: SP Edward Cabrera - Mia Round 2: SP Shane Baz - TB |
| 1st Team | 2nd Team |