| Week | Add | Drop |
| Pre-Season |
Round 1: OF Jake Fraley - Cin Round A: SP Shota Imanaga - ChN Round B: OF Austin Meadows - F/A |
Round A: SP Kyle Wright - KC Round B: C Danny Jansen - Bos |
| Week 1 |
Round 2: RP Hector Neris - Hou |
Round 2: RP Jose Leclerc - Tex |
| Week 2 |
Round 1: SP Paul Blackburn - NYN Round 2: 1B Giovanny Urshela - Atl |
Round 2: SP Tyler Wells - Bal |
| Week 3 |
Round 2: OF Esteury Ruiz - Oak |
Round 2: RP Hector Neris - Hou |
| Week 4 |
Round 1: SP Mike Lorenzen - KC |
Round 1: 1B Giovanny Urshela - Atl Round 2: 1B Alex Kirilloff - Min |
| Week 5 |
Round 1: OF Wilyer Abreu - Bos Round 2: SS Amed Rosario - Cin |
Round 1: 2B Davis Schneider - Tor Round 2: SS Tim Anderson - Mia |
| Week 6 |
Round 1: RP Hector Neris - Hou Round 2: OF Max Kepler - Min | |
| Week 7 |
Round 1: SP Trevor Williams - Was Round 2: SP Alec Marsh - KC |
Round 1: OF Nelson Velazquez - KC Round 2: SP Mike Lorenzen - KC |
| Week 8 |
Round 1: 2B Miguel Vargas - ChA |
Round 1: OF Esteury Ruiz - Oak |
| Week 9 |
Round 1: 3B Jose Miranda - Min Round 1: 3B Jose Miranda - Min Round 2: SP Simeon Woods Richardson - Min |
Round 2: OF Jake Fraley - Cin |
| Week 10 |
Round 1: OF Matt Vierling - Det Round 2: SP Mitchell Parker - Was |
Round 1: RP Carlos Estevez - Phi Round 2: OF Max Kepler - Min |
| Week 11 |
Round 1: 2B Lenyn Sosa - ChA Round 2: SS Adael Amador - Col |
Round 1: 2B Jorge Polanco - Sea Round 2: SP Trevor Williams - Was |
| Week 12 |
Round 1: SS David Hamilton - Bos Round 2: SP Cal Quantrill - Col |
Round 1: 2B Edouard Julien - Min Round 2: SP Jordan Wicks - ChN Round 2: SS Adael Amador - Col |
| Week 14 |
Round 1: 3B Isiah Kiner-Falefa - Pit |
Round 1: 2B Lenyn Sosa - ChA |
| Week 15 |
Round 1: C Elias Diaz - SD |
Round 1: C Luis Campusano - SD Round 2: 3B Isiah Kiner-Falefa - Pit |
| Week 16 |
Round 1: RP Jeff Hoffman - Phi Round 2: 2B Xavier Edwards - Mia |
Round 1: SS Blaze Alexander - Ari |
| Week 18 |
Round 1: SP Andrew Painter - Phi Round 2: SS Marcelo Mayer - Bos |
Round 1: SP Cal Quantrill - Col |
| Week 22 |
Round 2: C Elias Diaz - SD |
| 1st Team | 2nd Team |
| Week 11 | |
| Atomic Punks | Double. D |
|
SP
Chris Bassitt
Tor |
SS
Blaze Alexander
Ari |