| Week | Add | Drop |
| Pre-Season |
Round 1: 1B Alex Kirilloff - Min Round 2: RP Elvis Peguero - Mil | |
| Week 1 |
Round 1: SP Jordan Hicks - SF Round 2: 2B Brice Turang - Mil |
Round 1: SP Matt Manning - Det |
| Week 2 |
Round 1: SP Graham Ashcraft - Cin |
Round 1: RP Elvis Peguero - Mil |
| Week 3 |
Round 1: SS Jose Caballero - TB Round 2: SP José Butto - NYN |
Round 1: SS Javier Baez - Det Round 2: SS Gavin Lux - LAD |
| Week 4 |
Round 1: SP Jameson Taillon - ChN Round 2: OF Daulton Varsho - Tor | |
| Week 5 |
Round 1: OF Brenton Doyle - Col Round 2: RP Joel Payamps - Mil |
Round 1: RP Abner Uribe - Mil Round 2: 1B Alex Kirilloff - Min |
| Week 6 |
Round 1: OF Wenceel Perez - Det Round 2: 3B Brett Harris - Oak |
Round 1: OF Sal Frelick - Mil Round 2: OF Jack Suwinski - Pit Round 2: RP Joel Payamps - Mil |
| Week 7 |
Round 1: C Tyler Soderstrom - Oak Round 2: RP Yennier Cano - Bal |
Round 2: 3B Luis Urias - Sea |
| 1st Team | 2nd Team |
| Pre-Season | |
| Bottom of the pack 15 | Dayton Marcos |
|
OF
Spencer Steer
Cin |
Round 5, 8th Pick (RP Clay Holmes NYA) |
| Pre-Season | |
| Bottom of the pack 15 | Wait Til This Year |
|
SP
Luis Castillo
Sea |
Round 4, 4th Pick (2B Jorge Polanco Sea) |
| Pre-Season | |
| Bottom of the pack 15 | The Shogun of Harlem |
|
Round 1, 10th Pick (3B Jake Burger Mia) Round 5, 10th Pick (C Jonah Heim Tex) |
OF
Kyle Schwarber
Phi |
| Week 6 | |
| Bottom of the pack 15 | Albuquerque Isotopes |
|
SP
Mitch Keller
Pit RP Devin Williams Mil |
RP
Jhoan Duran
Min |