| Week | Add | Drop |
| Pre-Season |
Round 1: RP Kevin Ginkel - Ari Round A: SP Ryan Pepiot - TB |
Round 1: SP Trevor Bauer - LAD Round A: SP Jack Flaherty - Det |
| Week 1 |
Round 1: RP Abner Uribe - Mil Round 2: 3B Ezequiel Duran - Tex | |
| Week 2 |
Round 1: SP Reynaldo Lopez - Atl Round 2: SS Colson Montgomery - ChA |
Round 1: SP Nestor Cortes Jr. - NYA Round 2: RP Kevin Ginkel - Ari |
| Week 3 |
Round 1: SP Yusei Kikuchi - Tor Round 2: RP James McArthur - KC |
Round 1: 3B Ezequiel Duran - Tex |
| Week 4 |
Round 1: OF Esteury Ruiz - Oak Round 2: SS Gabriel Arias - Cle |
Round 1: OF Walker Jenkins - Min Round 2: SS Colson Montgomery - ChA |
| Week 5 |
Round 1: SP Mitchell Parker - Was Round 2: SP Cade Horton - ChN |
Round 1: RP Abner Uribe - Mil Round 2: OF Chas McCormick - Hou Round 2: DH Mitch Garver - Sea Round 2: OF Esteury Ruiz - Oak |
| Week 6 |
Round 1: OF Richie Palacios - TB Round 2: 2B Willi Castro - Min |
Round 1: SS Gabriel Arias - Cle |
| Week 7 |
Round 1: 2B Luis Garcia - Was |
Round 1: SP Hunter Brown - Hou |
| 1st Team | 2nd Team |
| Pre-Season | |
| Reggie Jackson | Warning Track Power |
|
Round 1, 6th Pick (SP Pablo Lopez Min) Round 4, 6th Pick (SP Freddy Peralta Mil) |
2B
Jose Altuve
Hou |
| Pre-Season | |
| Reggie Jackson | Bumgaardians |
|
Round 2, 6th Pick (SP Zach Eflin TB) Round 3, 6th Pick (SP Bailey Ober Min) |
SP
Framber Valdez
Hou |
| Pre-Season | |
| Reggie Jackson | Santa’s Royal Giants |
|
OF
Dylan Crews
Was |
Round 4, 8th Pick (SS Ha-seong Kim SD) |
| Pre-Season | |
| Reggie Jackson | Santa’s Royal Giants |
|
OF
Jackson Chourio
Mil |
OF
Jazz Chisholm
Mia Round 3, 8th Pick (SP Ryan Pepiot TB) |
| Pre-Season | |
| Reggie Jackson | Wichita Wind Surge |
|
3B
Nolan Arenado
StL SS Anthony Volpe NYA SS Jordan Lawlar Ari |
SP
Zac Gallen
Ari Round 6, 7th Pick (SS Jeremy Pena Hou) Round 9, 7th Pick (C Bo Naylor Cle) |
| Pre-Season | |
| Reggie Jackson | Wichita Wind Surge |
|
C
Willson Contreras
StL |
Round 3, 7th Pick (OF Chas McCormick Hou) |
| Week 4 | |
| Reggie Jackson | Wichita Wind Surge |
|
1B
Paul Goldschmidt
StL SP Max Fried Atl OF Jazz Chisholm Mia 3B Royce Lewis Min |
1B
Josh Naylor
Cle SP Kutter Crawford Bos RP Emmanuel Clase Cle OF Lars Nootbaar StL |