| Week | Add | Drop |
| Pre-Season |
Round 1: RP Kevin Ginkel - Ari Round 2: SP Ryne Nelson - Ari Round A: SP Kyle Harrison - SF Round B: SP Cade Horton - ChN |
Round A: SS Paul DeJong - ChA Round B: 2B Adam Frazier - KC |
| Week 1 |
Round 1: RP Abner Uribe - Mil Round 2: 3B Trey Lipscomb - Was | |
| Week 2 |
Round 1: SP Edward Cabrera - Mia Round 2: SS Blaze Alexander - Ari |
Round 1: SP Ryne Nelson - Ari Round 2: SS Trevor Story - Bos |
| Week 3 |
Round 1: OF Joey Loperfido - Hou Round 2: SP Kyle Bradish - Bal |
Round 2: OF Leody Taveras - Tex |
| Week 4 |
Round 1: RP Devin Williams - Mil Round 2: OF Daulton Varsho - Tor |
Round 1: 3B Trey Lipscomb - Was Round 2: RP Abner Uribe - Mil |
| Week 5 |
Round 1: RP Hector Neris - ChN Round 2: RP Kevin Ginkel - Ari |
Round 1: RP Kevin Ginkel - Ari Round 2: SP Logan Allen - Cle |
| Week 6 |
Round 1: RP Joel Payamps - Mil Round 2: SP Alek Manoah - Tor |
Round 1: RP Kevin Ginkel - Ari Round 2: RP Joel Payamps - Mil |
| 1st Team | 2nd Team |
| Pre-Season | |
| Call to the Pen | Dark Horse |
|
Round 13, 10th Pick (OF Alex Verdugo NYA) Round 14, 10th Pick (OF Lourdes Gurriel Ari) |
Round 16, 4th Pick (1B Joshua Bell Mia) Round 17, 4th Pick (SP Reid Detmers LAA) Round 18, 4th Pick (C Alejandro Kirk Tor) Round 19, 4th Pick (3B Elehuris Montero Col) |
| Pre-Season | |
| Call to the Pen | Dark Horse |
|
SP
Blake Snell
SF 1B Peter Alonso NYN |
3B
Royce Lewis
Min SP Grayson Rodriguez Bal Round 1, 11th Pick (SS Jordan Lawlar Ari) |
| Pre-Season | |
| Call to the Pen | Nashville Standard Giants |
|
Round 2, 10th Pick (OF James Outman LAD) Round 12, 10th Pick (C Luis Campusano SD) |
OF
Michael Harris
Atl |
| Pre-Season | |
| Call to the Pen | Bottom of the pack 26 |
|
Round 1, 10th Pick (SP Jesus Luzardo Mia) Round 5, 10th Pick (SP Mitch Keller Pit) Round 10, 10th Pick (1B Carlos Santana Min) |
Round 16, 2nd Pick (OF Mitch Haniger Sea) Round 17, 2nd Pick (SP Reese Olson Det) |