| Week | Add | Drop |
| Pre-Season |
Round 1: RP Kevin Ginkel - Ari Round 2: OF Victor Scott - StL Round A: SP Yoshinobu Yamamoto - LAD |
Round 1: SP Garrett Crochet - ChA Round 2: OF MJ Melendez - KC Round A: SS Ronny Mauricio - NYN |
| Week 1 |
Round 1: 3B J.D. Davis - Oak Round 2: 3B Ezequiel Duran - Tex | |
| Week 2 |
Round 1: SP Yariel Rodriguez - Tor Round 2: OF Brenton Doyle - Col |
Round 1: SP Shane Bieber - Cle Round 2: 3B Ezequiel Duran - Tex |
| Week 3 |
Round 1: SP Jacob deGrom - Tex Round 2: SS Jose Caballero - TB |
Round 1: OF Victor Scott - StL Round 2: SP Jacob deGrom - Tex |
| Week 4 |
Round 1: SP José Butto - NYN Round 2: C Patrick Bailey - SF |
Round 1: SP Jesus Luzardo - Mia Round 2: 3B J.D. Davis - Oak |
| Week 5 |
Round 1: SP Graham Ashcraft - Cin Round 2: SP Keaton Winn - SF |
Round 1: RP Kevin Ginkel - Ari |
| Week 6 |
Round 1: SP John Means - Bal Round 2: SP Jacob deGrom - Tex |
Round 1: SS Brayan Rocchio - Cle Round 2: SP Keaton Winn - SF |
| 1st Team | 2nd Team |
| Pre-Season | |
| Whiz Kids | Fort Worth Panthers |
|
1B
Vinnie Pasquantino
KC |
Round 3, 4th Pick (SP Joe Ryan Min) |
| Pre-Season | |
| Whiz Kids | Bad Reputation |
|
SS
Junior Caminero
TB |
Round 1, 12th Pick (SS Carlos Correa Min) |
| Pre-Season | |
| Whiz Kids | The Plantation |
|
Round 14, 1st Pick (OF Kerry Carpenter Det) Round 15, 1st Pick (RP Kyle Finnegan Was) Round 18, 1st Pick (SP Seth Lugo KC) Round 19, 1st Pick (SP Frankie Montas Cin) |
Round 11, 8th Pick (OF MJ Melendez KC) |
| Pre-Season | |
| Whiz Kids | Natural Grass |
|
SS
Jordan Lawlar
Ari 1B Kyle Manzardo Cle |
Round 5, 7th Pick (3B Ke'Bryan Hayes Pit) Round 2, 12th Pick (SP Brayan Bello Bos) |
| Pre-Season | |
| Whiz Kids | Natural Grass |
|
Round 10, 1st Pick (SP Shota Imanaga ChN) |
RP
Jordan Romano
Tor |
| Pre-Season | |
| Whiz Kids | Irish Panthers |
|
RP
Kyle Finnegan
Was |
Round 5, 11th Pick (SP Bryce Miller Sea) |
| Pre-Season | |
| Whiz Kids | Schaumburg Boomers |
|
OF
Daulton Varsho
Tor SP Josiah Gray Was |
Round 1, 9th Pick (C Francisco Álvarez NYN) Round 10, 9th Pick (OF Chase DeLauter Cle) |
| Pre-Season | |
| Whiz Kids | San Francisco Sea Lions |
|
Round 7, 1st Pick (1B Michael Busch ChN) |
Round 3, 10th Pick (1B Andrew Vaughn ChA) |
| Pre-Season | |
| Whiz Kids | Natural Grass |
|
Round 9, 1st Pick (OF Jung Hoo Lee SF) |
SP
Dane Dunning
Tex |
| Pre-Season | |
| Whiz Kids | Fort Worth Panthers |
|
Round 11, 1st Pick (SP Hunter Brown Hou) |
C
Yan Gomes
ChN |
| Week 4 | |
| Whiz Kids | Schaumburg Boomers |
|
SP
Yariel Rodriguez
Tor |
3B
Brett Baty
NYN |
| Week 5 | |
| Whiz Kids | New Orleans Zephyrs |
|
C
Francisco Álvarez
NYN SS Jackson Holliday Bal OF Chase DeLauter Cle |
RP
Josh Hader
Hou OF Bryan Reynolds Pit |
| Week 6 | |
| Whiz Kids | Schaumburg Boomers |
|
SP
Walker Buehler
LAD 1B Andrew Vaughn ChA SP José Butto NYN SP Graham Ashcraft Cin OF Wyatt Langford Tex |
OF
George Springer
Tor 3B Alex Bregman Hou 1B Ryan Mountcastle Bal OF Connor Joe Pit OF Lars Nootbaar StL |