| Week | Add | Drop |
| Pre-Season |
Round 1: SP Seth Lugo - KC Round 2: SP Dane Dunning - Tex | |
| Week 1 |
Round 1: SP Jonathan Loaisiga - NYA Round 2: SP Luis Ortiz - Pit | |
| Week 2 |
Round 1: 1B Jared Walsh - ChA Round 2: 2B Brice Turang - Mil |
Round 1: OF Matt Wallner - Min Round 2: SP Jonathan Loaisiga - NYA Round 2: SP MacKenzie Gore - Was |
| Week 3 |
Round 1: OF Brandon Marsh - Phi Round 2: OF Jurickson Profar - SD |
Round 1: 2B Brendan Rodgers - Col Round 2: 1B Andrew Vaughn - ChA |
| Week 4 |
Round 1: SP Mike Lorenzen - Tex Round 2: SP Lance Lynn - StL | |
| Week 5 |
Round 1: SS Tyler Freeman - Cle |
Round 1: SP Luis Ortiz - Pit |
| Week 6 |
Round 1: OF Bryan De La Cruz - Mia |
Round 1: SP Kyle Hendricks - ChN |
| 1st Team | 2nd Team |
| Pre-Season | |
| PREPARATION + OPPORTUNITY | Dallas Cubans |
|
2B
Marcus Semien
Tex Round 16, 11th Pick |
SP
Kevin Gausman
Tor Round 3, 12th Pick (SP Sonny Gray StL) |
| Pre-Season | |
| PREPARATION + OPPORTUNITY | Cleveland Tate Stars |
|
2B
Zack Gelof
Oak |
Round 5, 5th Pick (1B Andrew Vaughn ChA) |
| Pre-Season | |
| PREPARATION + OPPORTUNITY | Dallas Cubans |
|
RP
Camilo Doval
SF |
Round 4, 1st Pick (OF Cedric Mullins Bal) |
| Pre-Season | |
| PREPARATION + OPPORTUNITY | Rays |
|
Round 15, 11th Pick (SP Frankie Montas Cin) Round 17, 11th Pick (C Ryan Jeffers Min) |
C
Endy Rodriguez
Pit |