| Week | Add | Drop |
| Pre-Season |
Round 1: 1B Joshua Bell - Mia Round A: SP Kyle Harrison - SF |
Round A: C Gary Sanchez - Mil |
| Week 1 |
Round 1: OF Mitch Haniger - Sea Round 2: 3B Dylan Moore - Sea | |
| Week 2 |
Round 1: SP Cody Bradford - Tex Round 2: SS Jose Caballero - TB |
Round 2: SS Geraldo Perdomo - Ari |
| Week 3 |
Round 1: SP Colin Rea - Mil |
Round 1: 3B Yoan Moncada - ChA |
| Week 4 |
Round 2: SP Jameson Taillon - ChN |
Round 1: SP Kodai Senga - NYN Round 2: OF TJ Friedl - Cin |
| Week 5 |
Round 1: OF Jurickson Profar - SD |
Round 1: RP Adbert Alzolay - ChN |
| Week 6 |
Round 1: 2B Josh Rojas - Sea |
Round 1: 3B Dylan Moore - Sea |
| 1st Team | 2nd Team |
| Pre-Season | |
| Hulmeville Hot Shots | Bernie Williams |
|
OF
Jorge Soler
SF 2B Marcus Semien Tex SP Joe Musgrove SD |
1B
Christian Walker
Ari SP Aaron Nola Phi OF Randy Arozarena TB |
| Pre-Season | |
| Hulmeville Hot Shots | Deputy Dawg |
|
SS
Trevor Story
Bos |
2B
Xander Bogaerts
SD |