| Week | Add | Drop |
| Pre-Season |
Round 1: RP Kevin Ginkel - Ari Round 2: OF Mickey Moniak - LAA Round A: OF James Wood - Was Round B: SS Jackson Merrill - SD |
Round A: C Freddy Fermin - KC Round B: 2B Wilmer Flores - SF |
| Week 1 |
Round 2: SP Reid Detmers - LAA | |
| Week 2 |
Round 1: SP Tyler Wells - Bal Round 2: SS Tyler Freeman - Cle | |
| Week 3 |
Round 1: OF Brenton Doyle - Col Round 2: OF Jesse Winker - Was |
Round 1: 1B Matt Mervis - ChN Round 2: 1B Ryan Noda - Oak |
| Week 4 |
Round 1: SP Erick Fedde - ChA |
Round 1: SP Tyler Wells - Bal |
| Week 5 |
Round 1: OF Pete Crow-Armstrong - ChN Round 2: SP Keaton Winn - SF |
Round 1: C Freddy Fermin - KC Round 2: OF Mickey Moniak - LAA |
| Week 6 |
Round 1: OF Max Kepler - Min Round 2: C Patrick Bailey - SF |
Round 1: SS Brayan Rocchio - Cle Round 2: RP Yuki Matsui - SD |
| 1st Team | 2nd Team |
| Pre-Season | |
| Tennessee Rats | Midnight Run |
|
RP
Devin Williams
Mil |
Round 5, 1st Pick (1B Jeimer Candelario Cin) |
| Pre-Season | |
| Tennessee Rats | Midnight Run |
|
Round 1, 8th Pick (OF Christopher Morel ChN) |
OF
Jackson Chourio
Mil |
| Pre-Season | |
| Tennessee Rats | New Orleans Crescent Stars |
|
Round 8, 8th Pick (SP Nestor Cortes Jr. NYA) |
SS
Anthony Volpe
NYA |
| Week 4 | |
| Tennessee Rats | Deputy Dawg |
|
SP
Zac Gallen
Ari 2B Colt Keith Det SS Jackson Merrill SD |
OF
Michael Harris
Atl SS Jordan Lawlar Ari SP Yoshinobu Yamamoto LAD |
| Week 6 | |
| Tennessee Rats | Midnight Run |
|
OF
Josh Lowe
TB SP Nick Lodolo Cin |
2B
Nolan Gorman
StL RP Emmanuel Clase Cle |