| Week | Add | Drop |
| Pre-Season |
Round 1: SP Kenta Maeda - Det Round 2: SS Paul DeJong - ChA Round A: C Ethan Salas - SD |
Round A: C Patrick Bailey - SF |
| Week 1 |
Round 2: SP Paul Blackburn - Oak | |
| Week 2 |
Round 1: OF Jose Siri - TB Round 2: SP Dean Kremer - Bal | |
| Week 3 |
Round 1: SP Yusei Kikuchi - Tor Round 2: SS Nick Ahmed - SF |
Round 2: SS Paul DeJong - ChA |
| Week 4 |
Round 1: OF Roman Anthony - Bos Round 2: C Joey Bart - Pit |
Round 1: SP Kenta Maeda - Det Round 2: RP Griffin Jax - Min Round 2: OF Jack Suwinski - Pit |
| Week 5 |
Round 1: SP Mitchell Parker - Was |
Round 1: OF Will Benson - Cin Round 2: C Keibert Ruiz - Was |
| Week 6 |
Round 1: OF Jacob Young - Was Round 2: SS Zach Neto - LAA |
Round 1: 1B Ty France - Sea Round 2: SS Nick Ahmed - SF |
| Week 7 |
Round 1: 2B Luis Garcia - Was |
Round 1: SP Chris Bassitt - Tor |
| 1st Team | 2nd Team |
| Pre-Season | |
| Bernie Williams | Hulmeville Hot Shots |
|
1B
Christian Walker
Ari SP Aaron Nola Phi OF Randy Arozarena TB |
OF
Jorge Soler
SF 2B Marcus Semien Tex SP Joe Musgrove SD |
| Pre-Season | |
| Bernie Williams | Midnight Run |
|
SP
Blake Snell
SF |
OF
Riley Greene
Det |
| Pre-Season | |
| Bernie Williams | Midnight Run |
|
RP
Emmanuel Clase
Cle |
SP
Blake Snell
SF C Francisco Álvarez NYN |
| Pre-Season | |
| Bernie Williams | New Orleans Crescent Stars |
|
Round 5, 11th Pick (RP Ryan Helsley StL) |
OF
Eloy Jimenez
ChA |