| Week | Add | Drop |
| Pre-Season |
Round 1: SP Lance Lynn - StL Round 2: SP JP Sears - Oak Round A: SP Shane Baz - TB |
Round A: SP Cristopher Sanchez - Phi |
| Week 1 |
Round 1: SP Brady Singer - KC Round 2: SP Colin Rea - Mil | |
| Week 2 |
Round 1: SP Tyler Anderson - LAA Round 2: SP Alec Marsh - KC | |
| Week 3 |
Round 1: OF Jurickson Profar - SD Round 2: SP Joe Boyle - Oak |
Round 1: SP JP Sears - Oak Round 2: SS Gavin Lux - LAD |
| Week 4 |
Round 1: 1B Ryan O'Hearn - Bal | |
| Week 5 |
Round 1: OF Mark Canha - Det |
Round 1: RP Adbert Alzolay - ChN |
| Week 6 |
Round 1: OF Brandon Marsh - Phi |
Round 1: OF Kerry Carpenter - Det |
| Week 7 |
Round 1: OF Mike Tauchman - ChN |
Round 1: OF Jung Hoo Lee - SF |
| 1st Team | 2nd Team |
| Pre-Season | |
| Ft Myers Bull sharks | 4 GAMERS |
|
C
William Contreras
Mil Round 13, 10th Pick (SP Brandon Woodruff Mil) |
C
Willson Contreras
StL Round 7, 4th Pick (OF Jung Hoo Lee SF) |
| Pre-Season | |
| Ft Myers Bull sharks | Whiz Kids |
|
Round 10, 6th Pick (OF Giancarlo Stanton NYA) |
2B
Colt Keith
Det |
| Pre-Season | |
| Ft Myers Bull sharks | Whiz Kids |
|
SP
Mike Lorenzen
Tex |
Round 2, 8th Pick (RP Jhoan Duran Min) |
| Pre-Season | |
| Ft Myers Bull sharks | Leviticus |
|
Round 2, 10th Pick (SP Freddy Peralta Mil) Round 3, 10th Pick (C Cal Raleigh Sea) Round 4, 10th Pick (2B Edouard Julien Min) Round 7, 10th Pick (OF Jack Suwinski Pit) |
SP
Cole Ragans
KC |
| Pre-Season | |
| Ft Myers Bull sharks | Built 4 Speed |
|
SS
Wander Franco
TB |
Round 18, 11th Pick (SS Gavin Lux LAD) |
| Pre-Season | |
| Ft Myers Bull sharks | Aberdeen IronBirds |
|
Round 1, 7th Pick (OF Byron Buxton Min) Round 1, 10th Pick (1B Vinnie Pasquantino KC) Round 11, 10th Pick (OF Colton Cowser Bal) |
OF
Wyatt Langford
Tex Round 18, 3rd Pick (3B Curtis Mead TB) |
| Pre-Season | |
| Ft Myers Bull sharks | The Plantation |
|
SP
Zach Wheeler
Phi Round 5, 10th Pick (SP Mitch Keller Pit) |
Round 2, 5th Pick (SS Dansby Swanson ChN) |
| Pre-Season | |
| Ft Myers Bull sharks | Dust Devils |
|
RP
Emmanuel Clase
Cle |
Round 4, 6th Pick (RP Adbert Alzolay ChN) Round 10, 6th Pick (OF Giancarlo Stanton NYA) |
| Pre-Season | |
| Ft Myers Bull sharks | Whiz Kids |
|
Round 6, 10th Pick (OF Masataka Yoshida Bos) |
SP
Zach Eflin
TB |
| Pre-Season | |
| Ft Myers Bull sharks | Built 4 Speed |
|
SP
Kevin Gausman
Tor Round 4, 7th Pick (SP Dylan Cease SD) |
OF
Evan Carter
Tex Round 9, 11th Pick (C Salvador Perez KC) |
| Pre-Season | |
| Ft Myers Bull sharks | Leviticus |
|
OF
Adolis Garcia
Tex |
Round 1, 7th Pick (OF Byron Buxton Min) Round 4, 7th Pick (SP Dylan Cease SD) |
| Week 2 | |
| Ft Myers Bull sharks | TJP Parrothead Frenzy |
|
SP
Luis Castillo
Sea OF Evan Carter Tex SP Shota Imanaga ChN |
3B
Eugenio Suarez
Ari SP Jeffrey Springs TB OF Michael Harris Atl |