| Week | Add | Drop |
| Pre-Season |
Round 1: 2B Jeff McNeil - NYN Round 2: 3B Nick Senzel - Was Round A: SP Kyle Harrison - SF |
Round 1: RP Kyle Finnegan - Was Round A: SP Freddy Peralta - Mil |
| Week 1 |
Round 1: OF Charlie Blackmon - Col | |
| Week 2 |
Round 1: SP Alec Marsh - KC Round 2: 1B Jared Walsh - ChA |
Round 1: SP Shane Bieber - Cle Round 2: 1B Kris Bryant - Col |
| Week 3 |
Round 1: SP Kyle Gibson - StL Round 2: SP Martin Perez - Pit |
Round 1: RP Jose Leclerc - Tex Round 2: SP Kyle Gibson - StL |
| Week 4 |
Round 1: SP Jake Irvin - Was Round 2: OF Jordan Beck - Col |
Round 1: SS Nick Ahmed - SF Round 2: OF Chase DeLauter - Cle |
| Week 5 |
Round 1: 1B Ty France - Sea Round 2: OF Brent Rooker - Oak |
Round 1: 1B Jared Walsh - ChA Round 2: OF Charlie Blackmon - Col |
| Week 6 |
Round 1: C Connor Wong - Bos Round 2: OF Nolan Jones - Col |
Round 1: C Henry Davis - Pit Round 2: OF Masataka Yoshida - Bos |
| Week 7 |
Round 1: SP Frankie Montas - Cin |
Round 1: SP Martin Perez - Pit |
| 1st Team | 2nd Team |
| Pre-Season | |
| Mama's Boys | Erie SeaWolves |
|
SS
Junior Caminero
TB OF Wyatt Langford Tex Round 1, 5th Pick (OF Dylan Crews Was) |
SS
Corey Seager
Tex |
| Pre-Season | |
| Mama's Boys | Chaos Creators |
|
RP
Mason Miller
Oak |
Round 2, 8th Pick (RP David Bednar Pit) Round 3, 8th Pick (SP Gavin Williams Cle) |
| Pre-Season | |
| Mama's Boys | Bottom of the pack 12 |
|
C
Willson Contreras
StL |
Round 6, 11th Pick (C Willson Contreras StL) Round 7, 11th Pick (SP Cristian Javier Hou) |