| Week | Add | Drop |
| Pre-Season |
Round 1: C Gary Sanchez - Mil Round 2: OF Aaron Hicks - LAA Round A: OF Hunter Goodman - Col Round B: SP Brandon Pfaadt - Ari |
Round A: C Riley Adams - Was Round B: 1B Jose Abreu - Hou |
| Week 1 |
Round 2: SP Zack Littell - TB | |
| Week 2 |
Round 1: SP Yusei Kikuchi - Tor Round 2: OF Charlie Blackmon - Col | |
| Week 3 |
Round 1: SP Colin Rea - Mil Round 2: OF Mitch Haniger - Sea | |
| Week 4 |
Round 1: OF Jesse Winker - Was | |
| Week 5 |
Round 1: OF Hunter Goodman - Col Round 2: OF Bryan De La Cruz - Mia |
Round 2: OF Aaron Hicks - LAA |
| Week 6 |
Round 1: SP Keaton Winn - SF Round 2: 2B Luis Rengifo - LAA |
Round 1: 3B Yoan Moncada - ChA Round 2: RP Jose Leclerc - Tex |
| Week 7 |
Round 1: SP Erick Fedde - ChA Round 2: 3B Jose Miranda - Min |
Round 1: RP Will Smith - KC Round 2: RP Hunter Harvey - Was |
| 1st Team | 2nd Team |
| Pre-Season | |
| Quad Cities River Bandits | Bottom of the pack 7 |
|
Round 4, 3rd Pick (2B Xander Bogaerts SD) |
OF
Spencer Steer
Cin |
| Pre-Season | |
| Quad Cities River Bandits | New York Lincoln Giants |
|
Round 1, 3rd Pick (1B Vinnie Pasquantino KC) |
3B
Josh Jung
Tex |
| Pre-Season | |
| Quad Cities River Bandits | Bottom of the pack 7 |
|
2B
Marcus Semien
Tex Round 5, 3rd Pick (OF Brandon Nimmo NYN) |
3B
Jose Ramirez
Cle |
| Pre-Season | |
| Quad Cities River Bandits | Built 4 Speed |
|
Round 7, 3rd Pick (C Bo Naylor Cle) Round 10, 3rd Pick (OF Jarred Kelenic Atl) |
OF
Jasson Dominguez
NYA 1B Kyle Manzardo Cle |
| Pre-Season | |
| Quad Cities River Bandits | Pirates |
|
Round 6, 3rd Pick (2B Jordan Westburg Bal) |
OF
Dylan Crews
Was |