| Week | Add | Drop |
| Pre-Season |
Round 1: RP Ronel Blanco - Hou Round 2: SP Ryne Nelson - Ari Round A: SP Ryan Pepiot - TB Round B: SP Michael King - SD Round C: SP John Means - Bal |
Round A: 3B Ezequiel Duran - Tex Round B: OF Kole Calhoun - F/A |
| Week 1 |
Round 1: C Travis d'Arnaud - Atl Round 2: SP Sean Manaea - NYN | |
| Week 2 |
Round 1: OF Micahel Taylor - Pit Round 2: SP Javier Assad - ChN | |
| Week 3 |
Round 1: OF Edward Olivares - Pit Round 2: OF Blake Perkins - Mil | |
| Week 4 |
Round 1: SS Gabriel Arias - Cle Round 2: RP Kirby Yates - Tex | |
| Week 5 |
Round 1: OF Pete Crow-Armstrong - ChN Round 2: 2B Luis Rengifo - LAA |
Round 1: OF Aaron Hicks - LAA Round 2: SP Ryne Nelson - Ari |
| Week 6 |
Round 1: OF Mark Canha - Det Round 2: SP John Means - Bal |
Round 1: OF Micahel Taylor - Pit Round 2: OF Edward Olivares - Pit |
| Week 7 |
Round 1: OF Jonny DeLuca - TB |
Round 1: SS Gabriel Arias - Cle |
| 1st Team | 2nd Team |
| Pre-Season | |
| Homestead Grays | Beane Ballers |
|
SP
Zac Gallen
Ari |
3B
Royce Lewis
Min |
| Pre-Season | |
| Homestead Grays | Rabble-Rousers |
|
Round 3, 9th Pick (OF Chas McCormick Hou) |
SP
Chase Silseth
LAA |
| Pre-Season | |
| Homestead Grays | Zephaniah |
|
Round 2, 9th Pick (SP Joe Musgrove SD) Round 4, 9th Pick (OF Jack Suwinski Pit) Round 5, 9th Pick (RP Clay Holmes NYA) Round 6, 9th Pick (3B Anthony Rendon LAA) |
SP
Jeffrey Springs
TB |