| Week | Add | Drop |
| Pre-Season |
Round 1: OF Sal Frelick - Mil Round 2: SP Shane McClanahan - TB Round A: SP Ryan Pepiot - TB |
Round A: 3B Carter Kieboom - Was |
| Week 1 |
Round 1: RP Garrett Whitlock - Bos Round 2: SS Oswaldo Cabrera - NYA | |
| Week 3 |
Round 1: SP Joe Ross - Mil Round 2: SS Jose Caballero - TB |
Round 2: SP J.P. France - Hou |
| Week 4 |
Round 1: SP Mike Lorenzen - KC Round 2: C Riley Adams - Was |
Round 1: SS Zach Neto - LAA Round 2: C Keibert Ruiz - Was |
| Week 5 |
Round 1: RP Joel Payamps - Mil Round 2: SP Keaton Winn - SF |
Round 1: SP Matt Manning - Det Round 2: 1B Jose Abreu - Hou |
| Week 6 |
Round 1: 2B Luis Rengifo - LAA Round 2: 2B Michael Massey - KC |
Round 1: OF Sal Frelick - Mil Round 2: RP Joel Payamps - Mil |
| Week 7 |
Round 1: SP Taj Bradley - TB Round 2: SP Chris Paddack - Min |
Round 1: SP Joe Ross - Mil Round 2: SP Keaton Winn - SF |
| Week 8 |
Round 1: SP JP Sears - Oak Round 2: RP Trevor Megill - Mil |
Round 1: 2B Michael Massey - KC Round 2: SP Frankie Montas - Mil |
| Week 9 |
Round 1: 3B Miguel Andújar - Oak Round 2: SP Bailey Falter - Pit |
Round 1: 2B Xander Bogaerts - SD Round 2: RP Garrett Whitlock - Bos |
| Week 10 |
Round 1: SP Ryan Weathers - Mia Round 2: C Patrick Bailey - SF |
Round 1: SS Oswaldo Cabrera - NYA Round 2: C Riley Adams - Was |
| Week 11 |
Round 1: RP José Soriano - LAA Round 2: SP Jake Irvin - Was |
Round 1: SP Chris Paddack - Min Round 2: SP Ryan Weathers - Mia |
| Week 12 |
Round 1: SP Miles Mikolas - StL Round 2: SS Paul DeJong - KC |
Round 1: SP JP Sears - Oak Round 2: RP Carlos Estevez - Phi |
| Week 13 |
Round 1: SP Hogan Harris - Oak Round 2: 3B Daniel Schneemann - Cle |
Round 1: SP Bailey Falter - Pit Round 2: SS Paul DeJong - KC |
| Week 14 |
Round 1: SP Landon Knack - LAD Round 2: OF Derek Hill - Mia |
Round 1: SP Hogan Harris - Oak Round 2: 3B Daniel Schneemann - Cle |
| Week 15 |
Round 1: SP Josh Winckowski - Bos Round 2: OF Max Schuemann - Oak |
Round 1: SP Landon Knack - LAD Round 2: SP Miles Mikolas - StL |
| Week 16 |
Round 1: SP Jose Quintana - NYN Round 2: OF Richie Palacios - TB |
Round 1: OF Derek Hill - Mia Round 2: SP Josh Winckowski - Bos |
| Week 18 |
Round 1: 2B Jeff McNeil - NYN Round 2: C Tyler Stephenson - Cin |
Round 1: OF Richie Palacios - TB Round 2: C Patrick Bailey - SF |
| Week 19 |
Round 2: 2B Rob Refsnyder - Bos |
Round 2: SP Mike Lorenzen - KC |
| Week 20 |
Round 1: OF Jake McCarthy - Ari Round 2: 3B Jonah Bride - Mia |
Round 1: RP Tanner Scott - SD Round 2: 2B Luis Rengifo - LAA |
| Week 22 |
Round 2: RP Albert Suarez - Bal |
Round 2: RP Jordan Romano - Tor |
| 1st Team | 2nd Team |
| Pre-Season | |
| NYSE: EA | Akron RubberDucks |
|
SP
Luis Castillo
Sea 3B Noelvi Marte Cin |
Round 2, 5th Pick (OF Anthony Santander Bal) Round 4, 5th Pick (RP Carlos Estevez Phi) |
| Pre-Season | |
| NYSE: EA | Horseheads Buffalos |
|
Round 4, 7th Pick (SP Sonny Gray StL) |
OF
Jazz Chisholm
NYA |
| Pre-Season | |
| NYSE: EA | Clinton LumberKings |
|
2B
Zack Gelof
Oak |
Round 5, 2nd Pick (1B Ryan Mountcastle Bal) |
| Pre-Season | |
| NYSE: EA | Akron RubberDucks |
|
Round 16, 7th Pick (1B Ryan Noda Oak) Round 17, 7th Pick (SS Brayan Rocchio Cle) Round 18, 7th Pick (OF Jo Adell LAA) Round 19, 7th Pick (RP Dany Jimenez Oak) |
Round 13, 5th Pick (1B Jose Abreu Hou) |
| Pre-Season | |
| NYSE: EA | Salt Lake Bees |
|
SS
Corey Seager
Tex |
2B
Ozzie Albies
Atl |
| Week 10 | |
| NYSE: EA | Salt Lake Bees |
|
OF
Evan Carter
Tex |
SS
Ezequiel Tovar
Col |
| Week 11 | |
| NYSE: EA | The Plantation |
|
OF
Anthony Santander
Bal |
SP
Brady Singer
KC |
| Week 12 | |
| NYSE: EA | Akron RubberDucks |
|
SS
Oneil Cruz
Pit RP Trevor Megill Mil SP Bobby Miller LAD |
DH
Marcell Ozuna
Atl SP Luis Castillo Sea SP Tanner Houck Bos |