| Week | Add | Drop |
| Pre-Season |
Round 1: SP Jared Jones - Pit Round 2: C Yan Gomes - ChN Round A: OF Jung Hoo Lee - SF Round B: SP Trevor Bauer - LAD |
Round A: 1B Joey Votto - Tor Round B: SP Chase Silseth - LAA |
| Week 1 |
Round 1: SP Brady Singer - KC Round 2: RP Jason Foley - Det | |
| Week 2 |
Round 1: SP Yariel Rodriguez - Tor Round 2: C Travis d'Arnaud - Atl |
Round 2: SP AJ Puk - Mia |
| Week 3 |
Round 1: SS Blaze Alexander - Ari Round 2: 2B Brandon Drury - LAA |
Round 2: C Yan Gomes - ChN |
| Week 4 |
Round 1: SP José Butto - NYN Round 2: SS Gabriel Arias - Cle |
Round 1: OF JJ Bleday - Oak Round 2: 3B J.D. Davis - Oak |
| Week 5 |
Round 1: SP Mitchell Parker - Was Round 2: 2B Josh Rojas - Sea |
Round 1: SS Brayan Rocchio - Cle Round 2: SP Mitchell Parker - Was |
| Week 6 |
Round 1: OF Tommy Pham - ChA |
Round 1: 2B Brandon Drury - LAA |
| Week 7 |
Round 1: SP Robert Gasser - Mil Round 2: 2B Nick Gonzales - Pit |
Round 1: SP José Butto - NYN Round 2: SS Gabriel Arias - Cle |
| 1st Team | 2nd Team |
| Pre-Season | |
| Whiz Kids | My Bad |
|
Round 2, 11th Pick (SP Dylan Cease SD) |
2B
Whit Merrifield
Phi |
| Pre-Season | |
| Whiz Kids | Glacier Range Riders |
|
OF
Nick Castellanos
Phi |
Round 2, 5th Pick (SP Cole Ragans KC) |
| Week 3 | |
| Whiz Kids | Surprise Saguaros |
|
SP
Cole Ragans
KC SP Max Meyer Mia OF Ceddanne Rafaela Bos SP Jared Jones Pit SP Yariel Rodriguez Tor |
SP
Aaron Nola
Phi OF Bryan Reynolds Pit SP Tanner Houck Bos OF JJ Bleday Oak |