| Week | Add | Drop |
| Pre-Season |
Round 1: SP Clarke Schmidt - NYA Round 2: C Gary Sanchez - Mil | |
| Week 2 |
Round 1: 2B Brendan Donovan - StL Round 2: SP Tyler Anderson - LAA | |
| Week 3 |
Round 1: SP Colin Rea - Mil Round 2: C Ivan Herrera - StL | |
| Week 4 |
Round 1: SP Edward Cabrera - Mia | |
| Week 5 |
Round 1: OF Hunter Goodman - Col |
Round 1: 1B C.J. Cron - F/A |
| Week 6 |
Round 1: 2B Willi Castro - Min Round 2: 3B Patrick Wisdom - ChN |
Round 1: 3B Anthony Rendon - LAA Round 2: 1B Joey Votto - Tor |
| Week 7 |
Round 1: RP Griffin Jax - Min |
| 1st Team | 2nd Team |
| Pre-Season | |
| High Point Rockers | Houston Colt 45,s |
|
Round 1, 7th Pick (SP Tanner Bibee Cle) |
SP
Julio Teheran
F/A |
| Pre-Season | |
| High Point Rockers | Twins Rock |
|
Round 2, 7th Pick (SS C.J. Abrams Was) Round 3, 7th Pick (3B Isaac Paredes TB) Round 4, 7th Pick (3B Ryan McMahon Col) |
SP
Cal Quantrill
Col |
| Week 4 | |
| High Point Rockers | Bad Reputation |
|
1B
Paul Goldschmidt
StL OF Kyle Schwarber Phi 2B Zack Gelof Oak |
SP
Jordan Hicks
SF SS Oneil Cruz Pit RP Alexis Diaz Cin |