| Week | Add | Drop |
| Pre-Season |
Round 1: SP Dane Dunning - Tex Round A: SP Yoshinobu Yamamoto - LAD Round B: OF Austin Meadows - F/A |
Round A: RP Will Smith - KC Round B: SP Kyle Wright - KC |
| Week 1 |
Round 1: RP Jason Foley - Det Round 2: RP Garrett Whitlock - Bos | |
| Week 2 |
Round 1: SP Paul Blackburn - Oak Round 2: 2B Brendan Donovan - StL |
Round 1: RP Tanner Scott - Mia Round 2: OF Max Kepler - Min |
| Week 3 |
Round 2: OF Esteury Ruiz - Oak |
Round 2: SP Tyler Wells - Bal |
| Week 4 |
Round 1: SP Jameson Taillon - ChN Round 2: C Riley Adams - Was |
Round 2: SP Brandon Pfaadt - Ari |
| Week 5 |
Round 1: OF Jurickson Profar - SD Round 2: 2B Josh Rojas - Sea |
Round 1: OF Chas McCormick - Hou Round 2: 3B Anthony Rendon - LAA |
| Week 6 |
Round 1: C Danny Jansen - Tor Round 2: OF Max Kepler - Min |
Round 1: C Riley Adams - Was Round 2: OF Esteury Ruiz - Oak |
| Week 7 |
Round 1: SP Cole Irvin - Bal |
Round 1: SP Dane Dunning - Tex |
| 1st Team | 2nd Team |
| Pre-Season | |
| Stay Frosty | The Shogun of Harlem |
|
3B
Jose Ramirez
Cle Round 3, 1st Pick (SP Joe Musgrove SD) |
SS
Bo Bichette
Tor 3B Noelvi Marte Cin |