| Week | Add | Drop |
| Pre-Season |
Round 1: SS Gavin Lux - LAD Round 2: SP Logan Allen - Cle | |
| Week 1 |
Round 1: SP Clarke Schmidt - NYA Round 2: RP Ronel Blanco - Hou | |
| Week 2 |
Round 1: 3B Jared Triolo - Pit Round 2: SP Sean Manaea - NYN | |
| Week 3 |
Round 1: SS Tyler Freeman - Cle Round 2: OF Brandon Marsh - Phi |
Round 1: SS Gavin Lux - LAD Round 2: SS Gavin Lux - LAD |
| Week 4 |
Round 2: 3B Patrick Wisdom - ChN |
Round 2: 3B Jared Triolo - Pit |
| Week 5 |
Round 1: SP Shane Baz - TB Round 2: OF Jurickson Profar - SD |
Round 1: SP Logan Allen - Cle Round 2: SP Garrett Crochet - ChA |
| Week 6 |
Round 1: OF Wenceel Perez - Det |
Round 1: OF James Outman - LAD |
| 1st Team | 2nd Team |
| Pre-Season | |
| Dave's Destroyers | George Brett |
|
1B
Yandy Diaz
TB Round 7, 11th Pick (SS Ha-seong Kim SD) |
1B
Paul Goldschmidt
StL Round 16, 12th Pick (SP Andrew Abbott Cin) |
| Pre-Season | |
| Dave's Destroyers | Chaos Creators |
|
OF
Christian Yelich
Mil Round 8, 11th Pick (SP Eduardo Rodriguez Ari) |
3B
Nolan Arenado
StL |
| Pre-Season | |
| Dave's Destroyers | The Midnight Express |
|
Round 5, 11th Pick (RP Clay Holmes NYA) |
SP
Brandon Woodruff
Mil Round 19, 5th Pick (SP Garrett Crochet ChA) |